Posted on 08/31/2020 8:54:07 AM PDT by BenLurkin
Researchers from the University of Alberta described the drug as a protease inhibitor, which works by interfering with a virus’ ability to replicate and therefore ending the infection.
Lemieux said the drug was initially developed to prevent coronavirus infection in cats, which can result in the viral disease feline infectious peritonitis (FIP). She said research into its potential use in humans began during the SARS outbreak in 2003.
To do this, the research team synthesized the drug’s compounds and tested them against SARS-CoV-2 – the virus that causes COVID-19 – in test tubes and in human cell cultures.
Because the drug has already been used to treat cats with coronavirus, Lemieux said they’re able to bypass the animal-testing phase in their research and move on to clinical trials for the drug.
Lemieux said she feels confident the drug will be effective in treating humans with COVID-19 in the future. In the meantime, she said they’re studying different formulations for the drug so it will be more accessible.
The University of Alberta researchers’ findings were published in the peer-reviewed journal “Nature Communications” on Thursday.
(Excerpt) Read more at ctvnews.ca ...
Simple solution to the pandemic,,,,Make HCQ and Azithromycin OTC drugs so anyone who develops a cough and/or fever can go the nearest drug store and self medicate with the drugs along with Zinc Sulfate with correct dosage within 48 hours of symptoms and pandemic over.,,,,,instead of waiting a few days to get tested and 5 days for the results,,,,if over 60 years of age,,,,you’re dead.
one side effect is you knock random stuff onto the floor
I know that might sound funny but I’ve been thinking about this for months. We vaccinate our cats against coronavirus and have for decades. Made me wonder how they can’t look at why that vaccination works—what exactly it does.
Maybe that’s a long shot. Plus I’m not interested in taking any vaccine for Covid. No way.
I couldn’t work from home while taking it because I kept walking on my keyboard.
Cat Scratch Fever.
“Lemieux said the drug was initially developed to prevent coronavirus infection in cats”
“Lemieux” Wasn’t that how the cats meow’d in the Pepe LePew Cartoons.
Damn, got it backwards:
It was the cows, they would say LeMoooo.
no chit
thats a good juan
yes.
Caught it from the kitty next door.
Media claiming “Trump said to take cat medicine” in 3....2....1....
Does “the drug” have a name?
Several names{?}
“Feline infectious peritonitis, a fatal coronavirus infection in cats, was successfully treated previously with a prodrug GC376, a dipeptide-based protease inhibitor.
“Here, we show the prodrug and its parent GC373, are effective inhibitors of the Mpro from both SARS-CoV and SARS-CoV-2 with IC50 values in the nanomolar range. Crystal structures of SARS-CoV-2 Mpro with these inhibitors have a covalent modification of the nucleophilic Cys145.
” NMR analysis reveals that inhibition proceeds via reversible formation of a hemithioacetal. GC373 and GC376 are potent inhibitors of SARS-CoV-2 replication in cell culture.
“They are strong drug candidates for the treatment of human coronavirus infections because they have already been successful in animals. The work here lays the framework for their use in human trials for the treatment of COVID-19.”
Purrfect Treatment!
“... works by interfering with a virus’ ability to replicate and therefore ending the infection”
Just like HCQ, Invermectin, or Quercetin with Zinc.
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