Dr Louis P Coates
May 14 at 11:18 PM ·
Coronavirus Update 5/15/2020 - BTHO COVID-19
So today at the time of this writing there are 27,246 new cases today with 1715 deaths. Today’s mortality rate is at 6.29%. We also have 16,240 in critical condition still high so the fatality numbers will likely stay high a while longer. I was thinking the critical care number would start coming down soon. Today the overall mortality rate rose a little to 5.92%.
We also have now had 318,027 people recovered from this virus and should now have some degree of immunity from this horrific disease.
Locally, in Texas cases are relatively flat. We had 1482 new cases and 64 new deaths with a steady mortality rate of 2.8%.
Because antibody testing is being added to the numbers we are monitoring active cases. So we have 18,645 barely up from 18,355 active cases in Texas. The number of active cases is slightly increasing. In addition we have 24,600 recovered now. So active cases are very stable.
We are still many times under both the number of hospital beds and ICU beds needed. Hospital beds currently needed 1,289 with 28,634 available, in addition 358 ICU beds are needed and 2,260 available. So yes we should be open as there is no way to completely get rid of the virus. We must learn to coexist with it. Do not live in fear but respect the virus and take necessary precautions.
Today in Dallas county with 236 new cases and 6 deaths. Harris county with 196 new cases and 5 new deaths. Collin county with 15 new cases and 1 new death. Denton county with 21 new cases and no new deaths. Tarrant county with 266 new cases and 5 new death. Brazos county with 14 new cases and no new deaths. Travis county with 57 new cases and 2 new deaths. Fort Bend county with 48 new cases and no new deaths. Also Bexar county with 34 new cases and one new death.
For the newbies we are predicting an overall fatality rate somewhere in the 0.3 to 0.7 range when we finally correct the denominator. The real question is just how much of the population is already infected 2%, 5%, 10% etc.
New study in Russia shows potential benefit for NAC
A new study by Russian medical researchers suggests that deficiency of endogenous glutathione could also be another influencing factor of the degree of susceptibility by individuals towards the SARS-CoV-coronavirus that causes the deadly COVID-19 disease. Glutathione is naturally made in the human body and it can be supplemented in the body via supplementation with NAC or N-Acetyl Cysteine as it is a precursor for Glutathione production in the body.
Deficiency of glutathione has already been demonstrated through past studies to be associated with a growing number of chronic diseases including diabetes. asthma, autoimmune disorders, heart and lung diseases. As a person ages, glutathione levels typically falls and men also tend to have lower glutathione levels than women as they age. All of those sound familiar as they should as they are all risk factors for Covid-19. In addition another correlation is more men 60% get infected than women.
Glutathione is also a potent anti-oxidant that has also demonstrated antiviral properties in past studies. Not only does it help with oxidative stress it also decreases inflammation while helping boost the functions of immune cells. Knowing that NAC is a precursor for glutathione it should help fix all of these issues.
“Furthermore the antiviral effect of glutathione is clearly non-specific, since GSH is known to inhibit replication of various types of viruses, and therefore there is reason to believe that glutathione is also active against the novel coronavirus infection. Our observations demonstrate that patients with moderate-to-severe COVID-19-infection have lower levels of glutathione, higher ROS levels, and greater ROS/GSH ratio than patients with a mild illness suggesting that coronavirus SARS-CoV-2 cannot actively replicate at higher levels of cellular glutathione, and a lower viral load is manifested by milder clinical symptoms. This makes glutathione a promising drug for etiological treatment of various viral infections.”
https://www.researchgate.net/publication/340917045_Endogenous_deficiency_of_glutathione_as_the_most_likely_cause_of_serious_manifestations_and_death_in_patients_with_the_novel_coronavirus_infection_COVID-19_a_hypothesis_based_on_literature_data_and_ow
https://www.thailandmedical.news/news/breaking-covid-19-research-russian-study-indicates-that-glutathione-deficiency-affects-covid-19-susceptibility,-nac-supplements-helps
Another hydroxychloroquine study which helps give some answers?
This is a preliminary report on a study at NYU. This study examines adding zinc to hydroxychloroquine and zithromax. The reason I mention it is because that is what we are doing in clinical practice but the zinc is missing from most of the other studies. Remember that HCQ is a zinc ionophore and it allows zinc to get inside the cell where it can inhibit replicase. This enzyme is what allows the virus to reproduce itself. So not enough zinc than it can’t work. Zinc is very important and is being left out of most of the studies but we are using it in clinical practice and seeing anecdotal results.
So in this study 411 patients given zinc along with the malaria medicine hydroxychloroquine and the antibiotic azithromycin for five days were 44% less likely to die and 50% more likely to be discharged home than a comparison group of 521 patients who didn’t get the zinc supplement. Thus, this shows you need the zinc to get the better results.
https://www.medrxiv.org/content/10.1101/2020.05.02.20080036v1
In addition the NIH is starting a study of 2,000 patients with mild to moderate Coivd-19. This is a much needed study but unfortunately it appears to be HCQ/zithromax vs placebo. I don’t see where they are using zinc in this study either.
https://www.nih.gov/news-events/news-releases/nih-begins-clinical-trial-hydroxychloroquine-azithromycin-treat-covid-19
Here is a repost of the supplements we have discussed to have potential benefits.
Quercetin from 250mg up to 1g twice per day Remember this is a Zinc ionophore.
Vitamin D3 Take this for sure if you are deficient and I now recommend taking it as long as your values are not too high.
Sleep greater than 8 hours per night
CoQ10 100-300mg per day: a potent antioxidant that potentially helps balance oxidative stress, increase vasodilation, prevent clot formation and decrease vasoconstriction.
Zinc any amount is probably good but take what you can tolerate without making you feel bad up to 40mg. You do not want to be Zinc deficient as it is how many drugs like HCQ work.
Melatonin 1mg to 10mg at night. Take what you can tolerate and what helps you sleep without making you feel drugged or tired in the morning.
N-acetylcysteine (NAC) - 600mg twice per day shown to decrease severity of influenza, improve lung functions, antioxidant properties and help with mental disorders.
Vitamin C 250mg to 500mg twice per day. Effects debatable in oral form but IV did help in China. But is proven to strengthen immune system
Green Tea either drink some or 1 pill per day alternate zinc ionophore if you don’t have or don’t take Quercetin
As always the information and understanding of COVID-19 is changing rapidly. This information is for education purposes only and you should never make changes to your health without consulting your personal physician. Make a virtual appointment with your physician and discuss your health and the best possible treatment plan for you. It is also important to reiterate that there are no clinically evidence-based integrative prevention or treatment strategies for COVID-19 infection.
Let’s all keep praying for all that are ill with this virus in the world.
Gig’em!
Was about to ping you, but see (shoulda known :) that you’re already here.
My liposomal VitC has glutathione and I also have ordered Liposomal Glutathione.