[RummyChick]

fred hutch guy

https://twitter.com/trvrb

Trevor Bedford ✔ @trvrb I wanted to address the hypothesis put forward in Korber et al (https://www.biorxiv.org/content/10.1101/2020.04.29.069054v1 …) that the mutation in spike protein D614G causes an increase in transmissibility of SARS-CoV-2 virus. I find this hypothesis to be plausible, but far from proven. 1/16 Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 We have developed an analysis pipeline to facilitate real-time mutation tracking in SARS-CoV-2, focusing initially on the Spike (S) protein because it mediates infection of human cells and is the... biorxiv.org

[RummyChick]

Trevor Bedford
@trvrb
·
19h
Overall, I would refer everyone to
@edyong209
‘s piece on handling uncertainty during the pandemic (https://theatlantic.com/health/archive/2020/04/pandemic-confusing-uncertainty/610819/). I don’t agree with takes that there is “no evidence” that G is more transmissible. There is some evidence, but it’s far from conclusive. 15/16