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AS FOR HYDROXYCHLOROQUINE, HERE IS HER THESIS:

As a pharmacist, Chiusolo next evaluated the use of hydroxychloroquine to treat SARS-CoV-2, which in some cases has been found to reduce hospitalizations from the virus. Hydroxychloroquine is currently in use for the treatment of autoimmune diseases worldwide, such as lupus and rheumatoid arthritis, and has been used for years to treat malaria.

She said that in addition to the drug’s antiviral and immunomodulatory effect, it binds to the ferriprotoporphyrin of the ecgonine methyl ester (EME), blocking the key enzyme of malaria. “So, I thought this same mechanism could be used against SARS-CoV-2... Indeed, a study by a Chinese university shows that SARS-CoV-2 binds to the beta chain of hemoglobin, inhibiting EME metabolism.”

Ferriprotoporphyrin is the group responsible for the oxygen binding of hemoglobin.

1 posted on 05/03/2020 7:23:38 AM PDT by SeekAndFind
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To: SeekAndFind

Chiusolo said that hydroxychloroquine could act as a prophylactic, preventing or limiting the symptoms of the disease while waiting for the formulation of the vaccine that specifically stimulates the antibody response of the body. She said it could make the patient immune to COVID-19 and/or limit its side effects.

AS for those who are impatient... sorry, you have to wait some more. According to her:

The Italian Medicines Agency (AIFA), the national authority responsible for drug regulation in Italy, has an approved trial of hydroxychloroquine on 2,500 patients, which will start in early July and focus on the use of hydroxychloroquine in prophylaxis, Chiusolo said. The study, for which preliminary data would be ready within 16 weeks, will look at whether the preventive intake of the drug decreases the probability of contracting COVID-19 when one comes directly into contact with a positive patient.


2 posted on 05/03/2020 7:25:18 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

Related articles:
https://s3-eu-west-1.amazonaws.com/itempdf74155353254prod/11938173/COVID-19_Disease__ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin_v2.pdf

https://www.washingtonpost.com/health/2020/04/22/coronavirus-blood-clots/


5 posted on 05/03/2020 7:28:46 AM PDT by rightwingcrazy (;-,)
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To: SeekAndFind

Thank you very much for this information. That seems very promising, especially in light of us learning more about how the virus actually works in the body.

As far as American “scientists” go, I don’t care what they say about absolutely anything at all, but especially on HC, because they have no credibility whatsoever.

It’s amazing that TDS has become an actual contagious mental disease, and they will kill you over it.


7 posted on 05/03/2020 7:34:32 AM PDT by chris37 (China's Gift wasn't born in a bowl of bat soup.)
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To: SeekAndFind

Lame stream media attack in 3,....2,....


9 posted on 05/03/2020 7:38:20 AM PDT by rktman ( #My2ndAmend! ----- Enlisted in the Navy in '67 to protect folks rights to strip my rights. WTH?)
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To: SeekAndFind
It seems that there are interests that do not want to hear anything positive about HCQ.

Motivations seem to be primarily financial or Trump hatred.

This was some of the best damn anecdotal evidence I've ever heard.

10 posted on 05/03/2020 7:42:04 AM PDT by Aevery_Freeman (AOC has the perfect face for the 'Rat Party - Hee-Haw)
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To: SeekAndFind

OANN had a female doctor from Florida on a few weeks ago - she explained it all very well...perhaps this Italian “discoverer” saw the broadcast...


12 posted on 05/03/2020 7:52:01 AM PDT by trebb (Don't howl about illegal leeches, or Trump in general, while not donating to FR - it's hypocritical.)
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To: SeekAndFind
COVID-19 damages the hemoglobin, impairing the ability of red blood cells to transport oxygen throughout the body

I've read this in a variety of places over the past week. Seems to me there's something to this.


17 posted on 05/03/2020 8:01:10 AM PDT by Cinnamontea
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To: SeekAndFind
such as the greater vulnerability of men – specifically male diabetics – to become seriously ill from the virus

This is the first time I have seen this explicitly stated anywhere - after 3 months of "news" coverage...

19 posted on 05/03/2020 8:07:55 AM PDT by kiryandil (Chris Wallace: Because someone has to drive the Clown Car)
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To: SeekAndFind

Well since she is from Italy maybe we can finally get someone to look at how hemoglobin disorders that are thought to have evolved from malaria deal with Covid 19..such as Thalessemia -seen in Italians..and Sickle cell seen in Africans


22 posted on 05/03/2020 8:13:48 AM PDT by RummyChick ( Yeah, it's Daily Mail. So what.)
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To: SeekAndFind

when you put

ecgonine methyl ester

into a search engine a lot of Cocaine articles pop up


24 posted on 05/03/2020 8:17:27 AM PDT by RummyChick ( Yeah, it's Daily Mail. So what.)
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To: SeekAndFind; neverdem; ProtectOurFreedom; Mother Abigail; EBH; vetvetdoug; Smokin' Joe; ...
It took over 100 year to figure out how aspirin works...
Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

The false positive rate was 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

If a quarantine saves just one child's or one old fart’s life, it's worth it.

25 posted on 05/03/2020 8:18:25 AM PDT by null and void (By the pricking of my lungs, Something wicked this way comes ...)
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To: SeekAndFind

Bookmark


26 posted on 05/03/2020 8:24:06 AM PDT by aquila48 (Do not let them make you care! Guilting you is how they control you.)
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To: SeekAndFind

Wow, even the Jerusalem Post is calling this drug “controversial”. Sigh.


32 posted on 05/03/2020 8:46:02 AM PDT by LibertarianLiz
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To: SeekAndFind

“The lung cells become the site of the cytokine cascade, an enormous immune response, which is responsible for the acute lung inflammation that characterizes COVID-19 pneumonia,”


Someday these dumbasses suffering from myopia will see the forest through the trees and realize that ground zero for the battle against SARS-CoV-2 is the lungs.

Hemoglobin effects & consequent organ damage are results of a major blood infection akin to sepsis. Early treatment in vulnerable patients would inhibit such complications, perhaps prevent them altogether (as in the cases of me & my wife).

SMH


37 posted on 05/03/2020 8:55:55 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: SeekAndFind

From the Chinese University paper (current version is 8): “This paper is only for academic discussion, the correctness of the theory needs to be confirmed by other experiments. According to the reader’s suggestion, the content of the drug-related efficacy analysis has been deleted. Due to the side effects of drugs, please consult a qualified doctor for detailed treatment information, and do not take the drug yourself.”


43 posted on 05/03/2020 9:08:38 AM PDT by Jim Noble (There is nothing racist in stating plainly what most people already know)
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To: SeekAndFind

Bookmark


68 posted on 05/03/2020 1:15:50 PM PDT by Irish Eyes
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To: SeekAndFind

Wonder how different things would be if HCQ cost $1000/pill and still had a patent.


69 posted on 05/03/2020 1:33:11 PM PDT by Chauncey Gardiner
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