As a pharmacist, Chiusolo next evaluated the use of hydroxychloroquine to treat SARS-CoV-2, which in some cases has been found to reduce hospitalizations from the virus. Hydroxychloroquine is currently in use for the treatment of autoimmune diseases worldwide, such as lupus and rheumatoid arthritis, and has been used for years to treat malaria.
She said that in addition to the drugs antiviral and immunomodulatory effect, it binds to the ferriprotoporphyrin of the ecgonine methyl ester (EME), blocking the key enzyme of malaria. So, I thought this same mechanism could be used against SARS-CoV-2... Indeed, a study by a Chinese university shows that SARS-CoV-2 binds to the beta chain of hemoglobin, inhibiting EME metabolism.
Ferriprotoporphyrin is the group responsible for the oxygen binding of hemoglobin.
Chiusolo said that hydroxychloroquine could act as a prophylactic, preventing or limiting the symptoms of the disease while waiting for the formulation of the vaccine that specifically stimulates the antibody response of the body. She said it could make the patient immune to COVID-19 and/or limit its side effects.
AS for those who are impatient... sorry, you have to wait some more. According to her:
The Italian Medicines Agency (AIFA), the national authority responsible for drug regulation in Italy, has an approved trial of hydroxychloroquine on 2,500 patients, which will start in early July and focus on the use of hydroxychloroquine in prophylaxis, Chiusolo said. The study, for which preliminary data would be ready within 16 weeks, will look at whether the preventive intake of the drug decreases the probability of contracting COVID-19 when one comes directly into contact with a positive patient.
Thank you very much for this information. That seems very promising, especially in light of us learning more about how the virus actually works in the body.
As far as American “scientists” go, I don’t care what they say about absolutely anything at all, but especially on HC, because they have no credibility whatsoever.
It’s amazing that TDS has become an actual contagious mental disease, and they will kill you over it.
Lame stream media attack in 3,....2,....
Motivations seem to be primarily financial or Trump hatred.
This was some of the best damn anecdotal evidence I've ever heard.
OANN had a female doctor from Florida on a few weeks ago - she explained it all very well...perhaps this Italian “discoverer” saw the broadcast...
I've read this in a variety of places over the past week. Seems to me there's something to this.
This is the first time I have seen this explicitly stated anywhere - after 3 months of "news" coverage...
Well since she is from Italy maybe we can finally get someone to look at how hemoglobin disorders that are thought to have evolved from malaria deal with Covid 19..such as Thalessemia -seen in Italians..and Sickle cell seen in Africans
when you put
ecgonine methyl ester
into a search engine a lot of Cocaine articles pop up
It took over 100 year to figure out how aspirin works...Bring Out Your Dead
Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.
The purpose of the Bring Out Your Dead ping list (formerly the Ebola ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.
The false positive rate was 100%.
At some point we may well have a high mortality pandemic, and likely as not the Bring Out Your Dead threads will miss the beginning entirely.
*sigh* Such is life, and death...
If a quarantine saves just one child's or one old farts life, it's worth it.
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Wow, even the Jerusalem Post is calling this drug “controversial”. Sigh.
The lung cells become the site of the cytokine cascade, an enormous immune response, which is responsible for the acute lung inflammation that characterizes COVID-19 pneumonia,
Someday these dumbasses suffering from myopia will see the forest through the trees and realize that ground zero for the battle against SARS-CoV-2 is the lungs.
Hemoglobin effects & consequent organ damage are results of a major blood infection akin to sepsis. Early treatment in vulnerable patients would inhibit such complications, perhaps prevent them altogether (as in the cases of me & my wife).
SMH
From the Chinese University paper (current version is 8): “This paper is only for academic discussion, the correctness of the theory needs to be confirmed by other experiments. According to the reader’s suggestion, the content of the drug-related efficacy analysis has been deleted. Due to the side effects of drugs, please consult a qualified doctor for detailed treatment information, and do not take the drug yourself.”
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Wonder how different things would be if HCQ cost $1000/pill and still had a patent.