Could you please comment on why the polio vaccine is no longer given orally? TIA
re polio vaccine by mouth
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Not off the top of my head. Inactivated polio vaccine (IPV) is the only polio vaccine that has been given in the United States since 2000. https://us-browse.startpage.com/do/proxy?ep=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&ek=643141745n484r4o58326p666247746863695535&ekdata=1757ed2f5d4a291356658f8d09301f4b
“IPV, unlike OPV, cannot reproduce itself (or replicate) and, therefore, cannot possibly revert back to natural polio. To make IPV, poliovirus is purified and killed with a chemical (formaldehyde). IPV elicits antibodies in the bloodstream, not the intestines. It prevents the virus from traveling through the blood to the brain or spinal cord, thereby preventing paralysis. In a sense, because the vaccine induces antibodies in the bloodstream, and not the intestines, IPV induces a “second line” of defense against infection” https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-details/polio-vaccine
This smells like a rabbit hole.