You do it with a microscope and perform various treatments or alterations. Have you ever heard of genetic engineering? Further details are NOYB.
Here is a publicly available tutorial on genetic engineering which explains the basics:
https://en.wikipedia.org/wiki/Genetic_engineering
re: “You do it with a microscope ... “
Let’s TRY this again: YOU CAN’T SEE IT WITH A MICROSCOPE.
The Coronavirus is ~120 nm diameter, visible light is 400 to 700 nm (blue to red light.)
Care to take another stab at this?