Skip to comments.Antioxidant in mushrooms may relieve features of 'pregnancy hypertension'
Posted on 02/21/2020 3:47:06 PM PST by ConservativeMind
Pregnancy hypertension, or Pre-eclampsia, is a complex disorder of pregnancy. Treatment of elevated blood pressure can manage the condition in the mother, but in severe cases delivery is needed, which can present a major problem to the baby if it is born prematurely.
Now, research have shown in a rat model that a natural diet?derived antioxidant L-ergothioneine can relieve some of the clinical symptoms of Pre-eclampsia. The hope is that the same will be in evidence in humans.
"Our research shows that treating rats with pre-eclampsia with the natural antioxidant L-ergothioneine reduced blood pressure, prevented fetal growth restriction and dampened production of the damaging substances released from the placenta during pre-eclampsia," says Dr. Cathal McCarthy, leader of this research.
In order to be able to make enough L-ergothioneine to eventually treat patients, the scientists are looking into ways of producing this compound efficiently in high amounts using yeast cell factories. Ergothioneine can be found in a wide variety of foods, but in particular in mushrooms, where amounts are relatively high compared to other foods.
"Today, ergothioneine is either made chemically or extracted from mushrooms, but at DTU Biosustain we are developing a method to make it biologically. This should lead to its much wider availability at competitive prices," says Douglas Kell, Associated Scientific Director at DTU Biosustain and Research Chair in Systems Biology Department of Biochemistry, University of Liverpool. At DTU Biosustain, Douglas Kell and his team work closely together with the group of Senior Researcher Irina Borodina to produce L-ergothioneine biologically using advanced genomic engineering.
Much evidence exists for L-ergothioneine's benefits in a variety of neurological and vascular disorders as well. Thus, L-ergothioneine appears to be a safe, natural diet?derived antioxidant whose therapeutic potential looks promising but remains to be validated in human clinical trials.
(Excerpt) Read more at sciencedaily.com ...
I despise the new collective (singular) noun with plural verb forms. Instead of Apple Computer is launching a new phone, they now say Apple Computer are launching a new phone. Annoying!
Anyway, look for shiitake, maiitake, or even Baby Bella/Portabellla over standard white mushrooms for the highest ergothioneine. White has 1/10 the amount as the first two listed and Baby Bella has 1/4 the amount of the first two.
In other News, “LSD consumes 25,000 times its own weight in excess reality”
I hope this pans out.
It would be terrible to go through a pregnancy while battling extreme high blood pressure at the same time.
It’s a race to see if the baby can be delivered before your head explodes :-/
Badger Badger Badger Badger
Snake, it’s a snake
Mushroom Mushroom Mushroom
It must be true. I LOVE mushrooms! And I’ve never had Pre-eclampsia,
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