Posted on 01/14/2020 7:37:50 PM PST by ConservativeMind
The prostates of older mice contain more luminal progenitor cells -- cells capable of generating new prostate tissue -- than the prostates of younger mice, UCLA researchers have discovered.
The observation, published in Cell Reports, helps explain why, as people age, the prostate tends to grow, leading to an increased risk for prostate cancer and other conditions.
"Understanding what's causing the prostate to grow with age helps us to consider strategies to prevent the expansion of these cells and possibly reduce a person's risk for prostate growth or disease," said Andrew Goldstein, member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and a UCLA assistant professor of urology and of molecular, cell, and developmental biology.
Most organs in the body -- including the kidneys, liver and spleen -- lose mass as people age, and bone and muscle mass tend to decrease over time.
The prostate, however, typically grows with age, which is why more than half of men over age 60 have benign prostatic hyperplasia, or BPH, in which the enlarged prostate impinges on the urethra, the organ that carries urine out of the bladder.
When the team looked more closely at the luminal cells, they discovered that older prostates contained more luminal progenitor cells. While only 6% of luminal prostate cells were progenitors in the younger mice, 21% of luminal cells in older mice were prostate progenitors.
(Excerpt) Read more at sciencedaily.com ...
As a PCa survivor any news relating to finding a way to stop this mess is welcome.
What’s with all the prostate postings? Just curious, that’s all.
As I age (86) I find I have to sit to piss to empty my bladder throughly ...
Thank you, Disambiguator. Thankfully, I am just posting for others while I am researching the topic.
I mention more about this, here:
https://www.freerepublic.com/focus/chat/3808236/posts?page=13#13
Look on the bright side — at least SOMETHING is growing bigger.
thanks for posting. I’m looking for things to shrink my prostate.
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