[Grampa Dave]

Wonder if the American Love affair with statins and low fat diets are possible factors here?:

In a recently published article in Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease, Isobel A. Scarisbrick, Ph.D., director of the Neuroregeneration and Neurorehabilitation Laboratory at Mayo Clinic’s campus in Rochester, Minnesota, and co-authors investigate the relationship between fat intake, exercise and myelin production in mice.

The roles that dietary fat intake and other external factors play in the production of oligodendrocytes and OPCs is not well-understood.

Although brain lipids have high fat content, consumption of a diet containing excess fats and sugars has been shown to be detrimental to CNS function. However, myelin assembly requires a significant amount of lipids, and lipids play an important role in glial cell myelination.

[dfwgator]

Is the Ketogenic diet good for multiple sclerosis?

https://www.medicalnewstoday.com/articles/323895.php#targetText=The%20ketogenic%20diet%20is%20low,for%20everyone%20with%20multiple%20sclerosis.&targetText=The%20ketogenic%20diet%20does%20offer,factors%20before%20trying%20the%20diet.

[pepsi_junkie]

Although brain lipids have high fat content, consumption of a diet containing excess fats and sugars has been shown to be detrimental ...

I'd look at the excess sugars as the problem before the fat. But that's just me.