[ConservativeMind]

I must admit I have been skeptical about this drug’s capacity for doing anything with depression, but if I knew someone with depression and on ineffective drugs, this is what I would encourage trying.

Sometimes, diet, exercise, sleep, and getting one’s life otherwise in order still leaves gaps that medicines can help address.

[BipolarBob]

I asked my street drug dealer about ketamine and he can't get the stuff. I guess it's back to meth and crack cocaine.

/s

[BBQToadRibs]

Medical Underwriter here. We consider it an opioid and for insurance won’t touch anyone with a 10’ pole using it. Seen too many people crash and burn on it. May as well play with fentanyl.

[tomkat]

In late 2018, researchers showed that naltrexone also blocks the antidepressant effects of ketamine, which led them to propose that ketamine must also bind to the same opioid receptors and thus concluded ..

Incorrectly, perhaps ?
Correlation and causation are two different critters.

just sayin'

[Rurudyne]

Better to do without. People have it in their minds that life shouldn’t suck and they’ve been sold a bill of goods. Not only does life frequently suck, even badly, it is okay if it does. It is okay if people are depressed and unhappy, if they do without or are poor.

[sockmonkey]

11 ear old drag kid demos snorting ketamine on the couch

https://twitter.com/i/status/1084332546895368192