Boss Tweed was strutting around the Garment District the last time a Republican won this district, but I’m sure she’ll raise money. That’s what Republican political campaigns do in NYC.
Not that long ago (but still too long) ! Part of the western Queens (then NY-6) portion sent one as recently as 1947-49 and upper central Queens briefly from 1952-53 (then NY-5). The Bronx portion of the district sent Republican Paul Fino until 1969 (then NY-24).