not poo pooing the articles you linked to- but i noticed that it’s not just taking the metforming that might add life age- but the articles states “AND lifestyle changes”- so how do we know it isn’t simply the lifestyle changes that added years to the people’s lives? Lifestyle changes can and does have dramatic changes to people’s health all by itself-
Are there studies that show metformin alone- without lifestyle changes, can increase life expectancy?
I tried (late wife’s supply), but even 250-500 mg did a job on the stomach. I’m just not cut out for metformin.