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Broccoli sprout compound may restore brain chemistry imbalance linked to schizophrenia (glutathione)
Science Daily ^ | May 8, 2019 | Source: Johns Hopkins Medicine

Posted on 07/07/2019 8:48:31 AM PDT by ConservativeMind

Researchers say they have characterized a set of chemical imbalances in the brains of people with schizophrenia related to the chemical glutamate. And they figured out how to tweak the level using a compound derived from broccoli sprouts.

The researchers found on average 4% significantly lower levels of the brain chemical glutamate in the anterior cingulate cortex region of the brain in people with psychosis compared to healthy people.

Glutamate is known for its role in sending messages between brain cells, and has been linked to depression and schizophrenia, so these findings added to evidence that glutamate levels have a role in schizophrenia.

Additionally, the researchers found a significant reduction of 3% of the chemical glutathione in the brain's anterior cingulate cortex and 8% in the thalamus. Glutathione is made of three smaller molecules, and one of them is glutamate.

"We are thinking of glutathione as glutamate stored in a gas tank," says Thomas Sedlak, M.D., Ph.D. "If you have a bigger gas tank, you have more leeway on how far you can drive, but as soon as you take the gas out of the tank it's burned up quickly. We can think of those with schizophrenia as having a smaller gas tank.

For their study, published in April 2018 in Molecular Neuropsychiatry, the researchers recruited nine healthy volunteers (four women, five men) to take two capsules with 100 micromoles daily of sulforaphane in the form of broccoli sprout extract for seven days.

They found that after seven days, there was about a 30% increase in average levels in the subjects' brains. For example, in the hippocampus, glutathione levels rose an average of 0.27 millimolar from a baseline of 1.1 millimolar after seven days of taking sulforaphane.

Sulforaphane is found in a variety of cruciferous vegetables.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine
KEYWORDS: broccoli
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To: ConservativeMind

Your do realize that the heating pad is increasing circulation, I presume.

That’s a tell right there.

My experience was the basis for a health recovery which saw over 60 symptoms reversed. I wrote about it because I believe that I stumbled upon the cause of western lifestyle disease ( it’s not what you think).


41 posted on 07/08/2019 1:40:41 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: logi_cal869

On the heating pad, she had always used one, but she described that the far infrared did far more than the standard ones ever did.

Congrats on the life changing experience!


42 posted on 07/08/2019 2:48:06 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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