For a predator the size of a Grizzly Bear, I’d want a full metal jacket bullet vs a hollow point, especially in a pistol. You might be able to get a good head shot, but odds are you’re going to be shooting into the body. There’s a lot of fur, skin and muscle to go through to get to a vulnerable spot. If you read the accounts of the professional hunters in Africa back before WWII, a lot of them relied on steel jacketed bullets on lion where the bullet had to get through the thick chest muscles.
Yes, but most states prohibit fmjs in the field. Also, fmjs were used 130 years ago since softs were notorious for failing to stay together. Now, except for ele, maybe buff, a good controlled expansion monometal or heavy jacketed soft(partition) does better than anything else.