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Japan team transplants stem cells into brain to treat Parkinson's
Agence France-Presse ^ | 9 Nov 2018

Posted on 11/10/2018 6:36:21 PM PST by Olog-hai

Japanese researchers said Friday they have transplanted stem cells into the brain of a patient in the first stage of an innovative trial to cure Parkinson’s disease.

The research team at Kyoto University injected induced Pluripotent Stem (iPS) cells — which have the potential to develop into any cell in the body — into the brain of a male patient in his fifties, the university said in a press release.

The man was stable after the operation, which was performed last month, and he will now be monitored for two years, the university added.

The researchers injected 2.4 million iPS cells into the left side of the patient’s brain, in an operation that took about three hours. If no problems are observed in the coming six months, they will implant another 2.4 million cells into the right side.

The iPS cells from healthy donors have been developed into the precursors of dopamine-producing brain cells, which are no longer present in people with Parkinson’s disease. […]

The human trial comes after an earlier trial involving monkeys. […]

iPS cells are created by stimulating mature already-specialized cells back into a juvenile state — basically cloning without the need for an embryo. …

(Excerpt) Read more at afp.com ...


TOPICS: Health/Medicine; Local News
KEYWORDS: japan; kyotouniversity; parkinsons; stemcells
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1 posted on 11/10/2018 6:36:21 PM PST by Olog-hai
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To: Olog-hai

Fascinating.

The only problem would be if the stem cells over grow or mutate, which I guess could cause convulsions or the like, but if it can truly cure Parkinson’s, it would be great.


2 posted on 11/10/2018 6:44:44 PM PST by struggle
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To: Olog-hai

Isn’t dopamine insensitivity also a problem with Parkinson’s?


3 posted on 11/10/2018 6:45:22 PM PST by LukeL
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To: struggle

I have a question.

If you were allowed to have a choice, would you choose a shorter but healthy life right up to the end, or a very long life fraught with the normal illnesses that accompany aging ?


4 posted on 11/10/2018 6:51:21 PM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: Olog-hai

Whatever happened to embryonic stem cells? At one time that was a bigger scam than global warming.


5 posted on 11/10/2018 6:54:32 PM PST by Moonman62 (Give a man a fish and he'll be a Democrat. Teach a man to fish and he'll be a responsible citizen.)
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To: UCANSEE2

“——or a very long life fraught with the normal illnesses that accompany aging ?”


I don’t know if you are questioning everyone——but that’s my choice-——life is precious.

.

.


6 posted on 11/10/2018 6:54:58 PM PST by Mears
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To: Olog-hai
The iPS cells from healthy donors have been developed into the precursors of dopamine-producing brain cells, which are no longer present in people with Parkinson’s disease. […]

Sounds good. But.... what if the healthy donor cells decide to quit producing dopamine once they are in your brain ?

Maybe the reason the your original brain cells quit producing dopamine is because of you, not the cells.

7 posted on 11/10/2018 6:55:38 PM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: Mears

Yes, I was throwing the question out to everyone.
Thank you, I appreciate your answer.


8 posted on 11/10/2018 6:57:42 PM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: UCANSEE2

I’d choose the first, as I have Type 1 diabetes anyway, so I’ll end up with one no matter what.


9 posted on 11/10/2018 6:59:56 PM PST by struggle
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To: UCANSEE2

I’ll take the long road, with the unknown.


10 posted on 11/10/2018 7:11:33 PM PST by waterhill (I Shall Remain, in spite of __________.)
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To: UCANSEE2

I’ll take Option 1 every time.


11 posted on 11/10/2018 7:12:54 PM PST by TADSLOS (I hate Russian Dolls. They are so full of themselves.)
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To: Olog-hai

Bah, hundreds of refugees could do this with their eyes closed.

(obvious sarcasm should be obvious...)


12 posted on 11/10/2018 7:36:49 PM PST by wastedyears (The left would kill every single one of us and our families if they knew they could get away with it)
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To: Olog-hai
This has been attempted before. And the result was less than stellar.

https://www.pressreader.com/usa/the-washington-post-sunday/20070624/282200826505588

Dr Robert Iacono tried this, with fetal stem cells, back in 1989, and since he couldn't find a hospital in the US that would permit it, he dragged his patient, one Max Truex, to a clinic in Zhengzhou, China, where he had no problem in "acquiring" fetal cells.

The Chinese and Iacono were somewhat casual about separating out the proper cells, and when the autopsy was performed, on Truex's brain, they found foetal teeth, hair, bone...

13 posted on 11/10/2018 7:52:40 PM PST by jonascord (First rule of the Dunning-Kruger Club is that you do not know you are in the Dunning-Kruger club.)
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To: UCANSEE2

I’ll take half and half, long healthy life free of pain and suffering then dying in my sleep...........

The Lord may have other plans for me though.

Which ever brings more Glory to my Savior, the Lord Jesus Christ, I know He will lead me through.


14 posted on 11/10/2018 7:53:56 PM PST by Romans Nine
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To: UCANSEE2

Quality of life doesn’t have to mean shorter... a full life is the key... all the time I don’t spend exercising can come off the top, and I will still be ahead... yolo baby.


15 posted on 11/10/2018 8:04:23 PM PST by teeman8r (Armageddon won't be pretty, but it's not like it's the end of the world.)
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To: Olog-hai

P.S. My reference to “you” and “your” was not meant to apply to you. It was to apply to a person with Parkinson’s disease, and that it could be their subconscious or body itself that decides to quit working properly.

The body seems to have a ‘mind’ of it’s own.


16 posted on 11/10/2018 8:28:05 PM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: UCANSEE2

Most likely host issues cause the disease but now they can monitor effectiveness of treatment and changes in transplanted cells...cells...we’ll see


17 posted on 11/10/2018 8:29:56 PM PST by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: Getready

I’m sure that’s all true, but...

Why do cells decide to quit producing dopamine ?

Why does one cell decide to be a hair cell and another a liver cell ?


18 posted on 11/10/2018 9:04:37 PM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: Getready
Most likely host issues cause the disease

Was just rereading your statement and I really agree with your using the phrase 'host issues'. That one phrase may mean more than we think.

19 posted on 11/10/2018 9:26:09 PM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: jonascord

The article indicates they used adult stem cells this time.


20 posted on 11/10/2018 9:29:34 PM PST by Jeff Chandler (Every time a lefty cries "racism", a Trump voter gets his wings.)
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