It looks like you should pick the males; unless you want the females too, and thus forego the future, full-grown squash plant from that particular flower:
https://www.thekitchn.com/my-favorite-sign-of-summer-squash-blossoms-220816
GARDEN FRITTATA
Ingredients: tb each butter and peanut oil or vegetable oil 8 eggs, beaten 2 tsp Dijon or coarse ground mustard 1/2 cup green pepper, cored and diced 1/3 cup white or red onion, diced (or 4 green onions, white part and tender green part, chopped) cup mushrooms, thinly sliced 1/2 cup broccoli, blanched and chopped 2 cups spinach, blanched/well drained 2 minced gar/cl 2 tb ea parsley and chives, freshly chopped S/p to taste 4 ounces shredded cheddar 1/3 cup garden tomato, seeded and diced
METHOD While 10-12" pan heats on moderate flame, whip eggs/mustard til blended but not frothy When pan is hot (drop of water sizzles), add the butter/oil combo When the butter stops foaming, add the peppers, onions and then the mushrooms; saute' 2 minutes Add broccoli, spinach, garlic and herbs and heat for about one minute