A .44 mag in a model 29 does not bother me but there is no way I would fire full power loads in a .50 S&W.
Now a Ruger Redhawk or Super Redhawk are pretty tame with hot .44 mag loads.
I have a Ruger Redhawk 44 magnum. Its what goes in my backpack when I go hiking or camping. The kick’s not bad at all on it. Of course being a Ruger, its built like a tank.
I have fired a 454 Casull in a Freedom Arms revolver, but the recoil was a bit more than I care for.
I won’t touch a 460 or 500 S&W even if someone paid me to do so.