The FReepers own Folding@Home group can make full use of this hardware, running protein folding simulations to advance medical research.
Almost all AR and VR software makes use of it.
And the plethora of Wall Street computer trading systems that run Linux will run with few modifications.
Doom, as noted above, and Solitare, see much less improvement ... but the cards cascade down REALLY fast when you win!
Another strain of software that will take advantage is Multimedia Encoding. Video and Photo editing software is multi-threaded. All that motion picture software intensive activity could enjoy an uplift from this architecture.
This will not replace some GPU-compute functions though, so the benefit in multi-media might be slightly greater than insignificant.