[BroJoeK]

"(And I don’t mean for this to be snarky, just an observation)."

Of course you do, your answer here, as elsewhere, is nonresponsive, even for those who can decode it.

[ifinnegan]

No. It’s not snarky.

If you don’t understand structure is function you are not a physical scientist, or don’t understand it.

I have known too many scientists who seem to think of amino acids or nucleotides as letters.

Structure is all we have.

[ifinnegan]

Both you should read this and the associated article it is based on.

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Regulatory Dynamism in Evolution
While the proteins stay mostly the same, the management evolves much faster.

https://biophilic.blogspot.com/2014/10/regulatory-dynamism-in-evolution.html

http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003771