The modified vancomycin needs further development so it can be tested in people to prove its safety and efficacy.
Moreover, Boger’s team made the drug through a lengthy, 30-step process, which limits yield.
He and colleagues are working on shortening that process.
Even with the current synthesis method, the new vancomycin should be medicinally useful, the study said.
It’s more than 10 times as potent as an earlier version that introduced two lethal modifications.
With the third lethal change, the altered vacomycin is more than 1,000 times as potent as standard vancomycin itself.(More information at news source)
The altered and modified vacomycin is more than 1,000 times as potent as standard vancomycin itself.
The recent modification currently requires a 30 step process, which limits its production and availability, and is still experimental.
Vancomycin has saved my life (or a limb, anyway) twice. Good stuff.
Hope it is around if I need it again.
Colloidal silver it is highly effective and killing all known bacteria and viruses over it and 650 have been demonstrated been known for thousands of years and yet the mainstream medical establishment will only except its use on topical as an internal agent it kills viruses and bacteria much more effectively as it disables their aerobic uptake and targets only single celled organisms I highly recommend using colloidal silver
It’s about time they really focused on antibiotics that attack bacteria in more than one way to prevent resistance.
Recent research has led scientists believe that some infectious bacteria quorum signal to each other and that when they reach a critical mass become much more virulent. In other circumstances they signal to one another to go into a dormant cyst phase to protect themselves when being overwhelmed. Short circuiting this process could also lead to better antibiotics.
As opposed to years of testing on animals, plus thousands of pages of FDA reviews, the FDA should act to make at least the 10X version available immediately to human patients who have no realistic option other than a quick death from sepsis. If you’re gonna die anyway in a few days, what’s the harm of trying an experimental drug?
Third world countries sell antibiotics ‘by the pill’... a system unintentionally designed to wipe out the usefulness of all antibiotics. Since they outnumber us, soon we’ll be back living and dying like we did in the early parts of the last century. All of us.
The article reports that dr boger says they still gotta get past the animal and these toxicity studies..these are very tall obstacles. The article as I remember said nothing about it being tested in humans yet...the metabolism of this new vancomycin congener needs to be studied...it may fine in the lab...but either in the blood or topically it could show unacceptable toxicites....still a loooooong way to go..
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