The altered and modified vacomycin is more than 1,000 times as potent as standard vancomycin itself.
The recent modification currently requires a 30 step process, which limits its production and availability, and is still experimental.
My Mom had VRE (vancomyicin resistant) kidney disease that ended her life.
My dad had a Penicillin resistant respiratory infection and the only 2 choices were Vancomycin or sulfur drugs. They thought his kidneys couldn’t take the exposure to sulfur, so they tried the Vanco - it helped him to regain consciousness, but couldn’t lick the infection entirely, but at least he was able to communicate his wishes, so they quit harassing me.