If you want your HDL to go up dramatically, take Niacin.
If you want to lower Triglycerides, lower your alcohol use.
Didn’t need to do either. First of all, I rarely drink any alcohol, and never did. All I had to do was go back to eating real food, including butter, whole milk, increased my protein, and stopped eating high glycemic and overly refined foods.
I will mention that the body processes the fructose in sugar and high fructose corn syrup that so many foods are drenched in these days, similar to the way alcohol is processed.
Both excessive fructose intake and excessive alcohol can result in fatty liver disease.
As I said, the change in diet resulted in raising my HDL, and lowering the Triglycerides as well as normalizing total and LDL cholesterol. Didn’t need any niacin therapy either - just nutritious food.