It can provide a measure of protection when downloading software from sites you're not familiar with.
But as always, be careful when downloading from untrusted sites!
Like all anti-virus software for OS X, it turns OFF GateKeeper to work so that IT can find the Trojans that may come in. I don't recommend using it. Most other Mac experts take the same approach to Mac anti-virus.
Apple's GateKeeper will recognize all known Trojans and their families of variants and warn the user before allowing them to download. It is a system level protection and operates without taking any system resources or making a hit on operations.
A/V is not a system level operator and needs the download to occur first and be loaded into some area of memory for scan, so on install, it de-activates GateKeeper to disable all such warnings. That is NOT a good thing.
Many of the other Mac Anti-Virus solutions are worse than the problems they are designed to prevent. . . adding performance hits that are unacceptable for little gain. As I said, they all turn off Apple's own native protections that are working quite well.
These are a MAJOR waste of space.