Good question!
Again (and unfortunately) Ayn Rand thought the “rational mind exercised in freedom” would/could supplant any belief in God.
All human endeavors are the result of the sovereign God’s allowance; all things have been established from the creation such-that (Ecclesiastes), there is nothing NEW we can devise or imagine.
That said, I have read Rand and find her prescience regarding this “time of man” deeply interesting as applied to the world-theater we now observe (I know...weasel words to say I’m not a Randian-liberterian).
But, when do we reconnect to “God has created and is sovereign” in the aspects of our lives? Again...a very interesting possible connection.