O, that this too too solid flesh would melt
Thaw and resolve itself into a dew!
Or that the Everlasting had not fix’d
His canon ‘gainst self-slaughter!
GEE It’s almost like there was a DESIGNER!
Hat tip yefragetuwrabrumuy
Just how would you deploy such a combination in drug form?
Interesting. I wonder what the mechanism of action is.
The penicillins work by inhibiting bacterial cell wall polymerization. Bacteria counter this with the beta-lactamase enzyme, which cuts open a ring structure in the penecillins, making them ineffective.
Erythromycin has a completely different mode of action. It stops protein synthesis by interacting with the ribosome. Bacteria have different ways of countering this.
I find the idea of a protein-lipid complex that restores antibiotic sensitivity to such widely different antibiotics in bacteria having such different mechanisms of resistance rather amazing. Too amazing, in fact. I’d really like to see more studies and find out what is really going on here. It’s possible that all of the antibacterial activity is due to the protein complex and none of the antibiotics are necessary at all. But since bacteria will still grow in breast milk, this protein complex must be at very low concentration in milk.
Never mind me here. I’m just thinking out loud, trying to figure this out. Maybe I should just read the paper...
sfl