[neverdem]

Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits

[neverdem]

Ping

[Texas Fossil]

Thanks for posting this.

It may be a bit over my head but will try to digest it later.

[kabumpo]

Of course, it has nothing whatsoever to do with their parenting. Let’s just throw Jules Henry’s studies out the window and treat everything with chemicals.

[Sir Napsalot]

>>> DNA methylation at some genetic sites was consistently altered for all individuals with ASD, and differences at other sites were specific to certain symptom groups. The number of DNA methylation sites across the genome was also linked to the severity of autism symptoms suggesting a quantitative relationship between the two.

In the paper, some genes were previously identified to be associated with ASD, and some new ones identified using the mehtylomics. Next step for these researchers is to see if the same genetic sites were also methlylated in other broader ASD patients (more complicated due to polymorphism). Still too early yet to draw conclusions.