I was hoping you were going for something deeper.
How fruitful is fruitful? Is three kids enough? How about four? How about 17? And if you have 17, are you “fruitful”? Have you “multiplied”? If the answer to either is “yes”, then how is using contraception a sin?
I’m reminded of the sadducees “if 7 women married a man, who’s husband is she in the resurrection”, trying to pick holes in the word of God.
To which Jesus told them “Ye do err, not knowing the scriptures, nor the power of God.”
The Bible doesn’t cover modern technology of course. It doesn’t say anything about euthanasia either but we know that euthanasia is an abomination against God.
That’s why someone who has actually read the Bible through with the Spirit of God leading them actually gets to know the personality of Jesus through it. Just like if you sat down and talked with an old wise guy for a few weeks, you might not hear his opinion on every thing, but you would still know his opinion on those things, because you know the man.