That’s a pretty heavy load for a pistol
For sure....you sure can use a Cowboy action revolver...I’ve heard (read) that there are some Rugers that could handle it (Blackhawk?).....the load is strong enough to stretch the backstrap on a revolver if it isn’t beefy enough. I think there may be a Taurus model or two that might handle it...
I’ve got scads of Cowboy actions and I’d NEVER try it in them. The only thing I KNOW that will safely shoot it without any damage is my Winchester 92 Trapper Takedown which has double receiver lugs...