States rights and the intent of the original republic was the loser in that war.
“Conceiving that an individual independence of the States is utterly irreconcileable with their aggregate sovereignty; and that a consolidation of the whole into one simple republic would be as inexpedient as it is unattainable, I have sought for some middle ground, which may at once support a due supremacy of the national authority, and not exclude the local authorities wherever they can be subordinately useful.
James Madison, Letter to G. Washington
Puleeze! You don’t like the USA? MOVE!
Slavery was the loser.