I hope not.
If Obama quits, the next in line is Joe Biden (VP), then Nancy Pelosi (Speaker of the House), then Daniel Inouye (President pro tempore of the Senate), then Hillary Clinton (Secretary of State).
Obama needs to wait until the Republicans take over the House and Senate. Then he can quit, but only if he takes Biden with him.
Well, if Obama steps down, you can bet Slow Joe is going to make naming a replacement VP Job #1. Having only two people between Hillary Clinton and the Big Chair is too close for comfort.