You may need to update that SW, or you may have a contracted something it didn't catch. Or a whole host of other issues, but based on what you've provided, that's a place to start.
You might also want to, if you don't already, have a CD bootable OS and AV software from which you can scan your system.
safe mode popped up a warning
worm.win32.skynet detected on your system blah blah
Does Windows do that? or is this malware?