My son owns a vintage 1965 Vox Bobcat and a Gibson SG and he too plays Guitar Hero and Rock Band constantly.
Although I must admit he is very good on both.
Kinda chuckling a bit ...
My own experience has been that actually having experience playing an instrument is a detriment to playing Guitar Hero. But full disclosure, after 5 minutes of GH, I’m thinking ‘I could pick up an actual instrument’.
My digitech rp3 has a play along feature ... plug in the iPod and off I go.