For anti-virus, consider AntiVir.
For anti-spyware, I recommend SuperAntiSpyware.
Comodo is a good firewall. It's what I use.
I forgot, I do have and run Super Anti Spyware also. Thanks for the comment on Comodo. I had doubts about Comodo since it is completely free.
I used to use that too but it kept making parts fall off of my car...