Ashkenazim have the highest average IQ of any ethnic group, scoring 12 to 15 points above the European average. They are also strongly represented in fields and occupations requiring high cognitive ability. For instance, European-origin Jews account for 27 percent of U.S. Nobel science prize winners but make up only about 3 percent of the U.S. population.
But the group is also associated with neurological disorders, including Tay-Sachs, Gaucher's, and Niemann-Pick. Tay-Sachs is a fatal inherited disease of the central nervous system. Sufferers lack an enzyme needed to break down fatty substances in the brain and nerve cells. Gauchers and Niemann-Pick are similar, often fatal diseases.
http://news.nationalgeographic.com/news/2005/07/0718_050718_ashkenazim.html