Some issues, like abortion, are non-negotiable. Either you understand that it is murder, or you don't.
If those that don't care or (heaven forbid) are pro-abortion, and don't mind throwing the innocent "under the bus," then I (and many like me) have no time for anything else they have to say, because their reasoning and/or conscience is in need of repair. It's that simple. If they don't get that issue, nothing else they have to say will matter, as statements from a person lacking such reasoning are suspect by definition.
Now, for other issues that are NOT bigger than politics, we can negotiate and at least agree to disagree if no common ground can be found.
Is that answer acceptable?
I don't consider abortion a 1% issue because it is part of one's fundamental and their view of rights and our country. If they are willing to let an entire class of citizen be killed, that belief spreads to much of their other philosophy. It shows the believe that one individual has the right over another's life, a completely anti-conservative value. Once you cross that line, there isn't much that isn't touched by this value (or lack thereof.)