p2138_ww2138 says it will be finished on 31 Dec 06....whatever that means...
A detailed explanation is found here:
http://fah-web.stanford.edu/cgi-bin/allprojects#2127
and scroll down to p2138.
"The villin headpiece is a fragment of the protein villin, and is formed from three helices which are packed together. Villin is a protein that helps maintain a mesh of fibers (made from the protein actin) that serves as a sort of skeleton for the cell."
In particular, p2138 is using an improved treatment for the electrostatic forces.
Here is what the villin protein looks like:
Kinda cute, for a protein.
Notice how curly the protein is? All proteins are rolled up inside the cell and must be uncurled to actually do anything. Stanford is doing detailed studies of this folding and unfolding, usually in the presense of water, sometimes with urea or or other molecules.
It is when these protein do NOT fold correctly that diseases can be manifested.