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Marijuana May Slow Alzheimer's
CBS News ^ | October 6th, 2006 | WebMD

Posted on 10/07/2006 9:24:11 AM PDT by cryptical

THC, the key compound in marijuana, may also be the key to new drugs for Alzheimer's disease.

That's because the marijuana compound blocks the formation of brain-clogging Alzheimer's plaques better than current Alzheimer's drugs.

The finding — in test-tube studies — comes from the lab of Kim Janda, Ph.D., director of the Worm Institute of Research and Medicine at Scripps Research Institute.

"While we are certainly not advocating the use of illegal drugs, these findings offer convincing evidence that THC possesses remarkable inhibitory qualities, especially when compared to [Alzheimer's drugs] currently available to patients," Janda says in a news release.

"Although our study is far from final, it does show that there is a previously unrecognized molecular mechanism through which THC may directly affect the progression of Alzheimer's disease."

Janda's team found that THC blocks an enzyme called acetylcholinesterase, which speeds the formation of amyloid plaque in the brains of people with Alzheimer's disease.

The Alzheimer's drugs Aricept and Cognex work by blocking acetylcholinesterase. When tested at double the concentration of THC, Aricept blocked plaque formation only 22 percent as well as THC, and Cognex blocked plaque formation only 7 percent as well as THC.

"THC and its analogs may provide an improved [treatment for] both the symptoms and progression of Alzheimer's disease," the researchers conclude.

The findings appear in the Aug. 9 online edition of the journal Molecular Pharmaceutics, a publication of the American Chemical Society.


TOPICS: Health/Medicine
KEYWORDS: addicted; callingdrleroy; wishfulthinking; wodlist
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To: catholicfreeper
The U.S. pays the Univ of Mississippi about $250K a year to grow about 6 acres of pot. Link.
21 posted on 10/07/2006 9:49:16 AM PDT by atomic_dog
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To: gov_bean_ counter

And alot of students at San Francisco State will be walking funny................


22 posted on 10/07/2006 9:50:14 AM PDT by stephenjohnbanker (Our troops will send all of the worlds terrorists to hell in a handbasket with no virgins!)
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To: cryptical
The headline is incorrect. They did not study marijuana. They studuied THC.

If some chemical compound found in gasoline cured acid reflux, would the headline read, "Drinking gasoline cures acid reflux"?

23 posted on 10/07/2006 10:20:56 AM PDT by robertpaulsen
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To: johnthebaptistmoore
Something similar actually happened:

"Las Vegas -- An initiative to legalize possession of up to 1 ounce of marijuana in Nevada might go up in smoke, after organizers forgot to file 6,000 petition signatures in southern Nevada."
-- Associated Press, June 24, 2004

24 posted on 10/07/2006 10:25:59 AM PDT by robertpaulsen
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To: gov_bean_ counter
Balance your brain chemicals all you want, but the final outcome is still the same.

By "final outcome" you mean slowing the onset of Alzheimer's?
25 posted on 10/07/2006 10:41:33 AM PDT by billybudd
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To: robertpaulsen
The headline is incorrect. They did not study marijuana. They studuied THC.

I'd guess that CBS News has an ombudsman that will take your complaint.

26 posted on 10/07/2006 11:11:20 AM PDT by cryptical (Wretched excess is just barely enough.)
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To: cryptical

MSM fan?


27 posted on 10/07/2006 11:12:51 AM PDT by Mojave
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To: Mojave
MSM fan?

Miss the point much? If he wants to complain about the headline, he can complain to the place that wrote it.

28 posted on 10/07/2006 11:19:19 AM PDT by cryptical (Wretched excess is just barely enough.)
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To: robertpaulsen

More godless socialist reductionist spew! It is not an herb they studied but a chemical compound? Yeah? One created by God and given to man! Receptors for that compound exist in your mind. Maybe you can design a new chemical compound to remove the receptors or block them so that nobody can alter their mind in a way you deem inappropriate.


29 posted on 10/07/2006 12:07:39 PM PDT by PaxMacian
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To: cryptical
If he wants to complain about the headline

MSM defenders such as yourself hate it when misstatements of facts are exposed. That's what happened, your disingenuous euphemisms notwithstanding.

30 posted on 10/07/2006 1:49:43 PM PDT by Mojave
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To: PaxMacian
It is not an herb they studied but a chemical compound? Yeah?

Yeah.

31 posted on 10/07/2006 1:52:32 PM PDT by Mojave
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To: Mojave
They studied THC or Tetrahydrocannabinol, a Cannabinoid
Sure, it is still the same compound whether synthesized
or extracted from the originating herbal source as gifted
from God at the very beginning of time. But, herbs don't
have any medicinal properties in RP's world. They are
reduced to powerful substances to fear for their toxicity.
Indeed, the ignorance expressed in failing to recognize the
reductionist methodology of newspeak is typical
of the frightened children of the dark who conjure DEAmen
to do their evil bidding.
32 posted on 10/07/2006 4:43:17 PM PDT by PaxMacian
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To: PaxMacian; robertpaulsen
But, herbs don't have any medicinal properties in RP's world.

If you're going to lie about robertpaulsen, at least have the decency to ping him.

33 posted on 10/07/2006 5:41:13 PM PDT by Mojave
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To: Mojave
That's what happened, your disingenuous euphemisms notwithstanding.

I don't think "disingenuous" or "euphemism" mean what you think they do, but thanks for playing.

34 posted on 10/07/2006 6:57:54 PM PDT by cryptical (Wretched excess is just barely enough.)
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To: cryptical

Thanks for losing, albeit ungraciously.


35 posted on 10/07/2006 8:22:05 PM PDT by Mojave
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To: Dan(9698)

and, whoa, you've got, like, the munchies all the time dude!


36 posted on 10/08/2006 7:33:34 AM PDT by stm (Katherine Harris for US Senate!)
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To: catholicfreeper

They are in Mississippi.


37 posted on 10/18/2006 11:25:40 AM PDT by Pharmboy ("I have more guns than I need, but less than I want." Sen. Phil Gramm)
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