I wonder if she is related to the Astor family which went down on the Titanic. Born in 1902 she would have been a contemporary.
Brooke Astor's father was at one time commandant of the Marine Corps. Vincent Astor was her third husband, and the son of the Colonel Astor who went down on the Titanic. After Vincent's death in 1959, Brooke devoted her time to supervising the trust that distributed the bulk of the Astor fortune to charity.
She married Vincent Astor who was the son of JJ Astor who went down on the Titanic. Vincent had a younger brother who was in utero on the Titanic. I believe (not sure) that Vincent (obviously a young boy) was not on the ship.
So Brooke never met her (third) father-in-law because he was lost at sea decades before she married into the Astor family.
She was married to Vincent Astor, son of John Jacob Astor the IV....who went down with the Titanic.