Studies are always difficult to interpret. Remember the Calcium D study that seemed to show that supplemental Calcium did not reduce the risk of fracture or increase bone density.
But it was found out after the results were interpreted that many of the control group were taking supplemental Calcium on their own accord, so there was little if any difference between the calcium intake of the control group and the target group.
Same thing might be said about Vitamin C. I am firmly in the camp that thinks mos humans realistically need between 6 and ten grams a day of C, if not more.
So the difference between somebody who only takes say 400 mg and somebody who takes 1500 mg might not be very great.
Also, any studies on E can only be considered totally preliminary. E is as big, if not a bigger family of vitamins than B. 4 or 5 tocopherols, and a bunch of tocotrienols.
It's interesting that one of the first recognized roles of Vitamin E is as a needed nutrient for fetal development, the name itself reflects that. Hence the name tos (Greek: childbirth), phero (Greek: to bring forth) and ol (alcohol).
I suspect you are correct. I have become a believer. I found out, quite by accident, that large doses of Vit C erased the pain of a shoulder injury. I believe it was a torn rotator cuff but I did not go to a doctor because I knew my only options from a doctor was surgery or drugs.
The injury occured about two years ago and my shoulder is healed. I have done much study about Vit C on the Internet and would love to find someone who uses intravenous Vit C, in case I, or a loved one ever needs it.
In Adele Davis' book, she recommended large doses of Vit C for pregnant women. My daughter did it and when she had her baby, she said a quiver came over her body and the baby slid out.
I won't say that was proof of anything but it certainly is worthy of further investigation and from what I read in the Internet, Vit C has been very beneficial for pregnant women and their babies.
When you are discussing vitamin supplementation using doses that are multiples of the current recommened dietary allowance, i.e. RDA, show me the studies.