Yeah, very possible. Likely, even.
i believe that you will find Thunderbird rather feature rich. A couple of dedicated Eudora users have made the switch and never looked back. There are (for example) features that permit the use of traditional webmail outlets, such as Yahoo!, Hotmail, Gmail, and others from inside the Thunderbird email client.
Yup -- I do something like that now using a combination of Eudora, and programs called YPOPs and Mailwasher. It'd be nice to have one program do it all, tho.
Yunz'll like it an'at < /Pittsburgese>