MS Office = Open Office
Adobe Sweet - as in writer or photoshop? for what 99.9% of people do in photoshop GIMP is just fine.
iTunes - I know of no windows users who use iTunes (though some I am sure exist)
BTW with Winde I have run MS Office, and Photoshop on Linux though I have never tried iTunes..
Open Office, I actually beleived that till I convinced the company to buy it at one point...
Photoshop/InDesign/Distiller-Acrobat Can similar stuff be done on Linux? Yes. Do companies feel like spending millions retraining people to use it? No.
iTunes.
iPod uses iTunes to populate the iPod with songs. There are a copy third party utilities that can also do it but iTunes is free and usually far more uptodate/compatible with the latest iPods. I can't imagine not using iTunes with an iPod though my Russian freind does this.
iTunes - I know of no windows users who use iTunes (though some I am sure exist)
OK, two.
But from what I've read, Crossover Office Pro can run Office, IE, iTunes, Adobe, etc. The bad thing is that it costs $$$--though I believe there are bulk discounts available. It's something I'm going to look at investing in when I get a computer and Linux back up and running.
As for running with Wine, I've been able to get the install to run but not the program.
Most of the programs I've been able to run are small install-executables, with FF being the notable exception.
Linspire actually has an iTunes clone called LSongs. It even incorporates internet radio using Shoutcast. That's how I listen to the Alex Jones Show.