I highly recommend NOD32 as an antivirus program, much less overhead than all the others out there, with excellent detection rates. Won't slow down your computer like Norton has a tendency to do. Webroot Spysweeper and PC Tools Spyware Doctor are excellent anti-spyware products, for best coverage run both at the same time. Zone alarm is great as a firewall.
I think it has succumbed to the common commercial software disease of alarmist teasers. It found a couple of changes to my hosts file and registry that other tools I use and trust have made, and did its best to alarm me into being scared that these changes meant that I was infected with a couple of seriously nasty trojans.
However it did its best to not give me enough useful information to follow up, and to scare me into buying it right away, to remove these dreadful threats. For both the trojans it claimed I had, none of the various other, more serious and specific, symptoms are present on my system.
This means that I cannot trust its alarms. It is more interested in selling me the full version than in providing an accurate assessment of the problem.
Googling around, the other uses and comments I found for Spyware Doctor seem consistent with this analysis.
Off it goes.