The end of 'Some Like it Hot'.
Jack Lemmon is in drag explaining to a man who wants to marry him that he's no good, he can't have kids, he smokes all the time.
Finally he takes off his wig and says..." I'm a man".
His suitor looks at him deadpan and says...." Nobody's Perfect".
Yup... THe whole movie, inexplicably ranked so highly by AFI, was just a set-up for that one line. And it still was worth it.