Posted on 10/24/2021 4:01:39 PM PDT by SoConPubbie
Background and purpose:
Cerebral venous sinus thrombosis (CVST) has been described after vaccination against SARS-CoV-2. The clinical characteristics of 213 post-vaccination CVST cases notified to the European Medicines Agency are reported.
Methods:
Data on adverse drug reactions after SARS-CoV-2 vaccination notified until 8 April 2021 under the Medical Dictionary for Regulatory Activities Term 'Central nervous system vascular disorders' were obtained from the EudraVigilance database. Post-vaccination CVST was compared with 100 European patients with CVST from before the COVID-19 pandemic derived from the International CVST Consortium.
Results:
In all, 213 CVST cases were identified: 187 after AstraZeneca/Oxford (ChAdOx1 nCov-19) vaccination and 26 after a messenger RNA (mRNA) vaccination (25 with Pfizer/BioNTech, BNT162b2, and one with Moderna, mRNA-1273). Thrombocytopenia was reported in 107/187 CVST cases (57%, 95% confidence interval [CI] 50%-64%) in the ChAdOx1 nCov-19 group, in none in the mRNA vaccine group (0%, 95% CI 0%-13%) and in 7/100 (7%, 95% CI 3%-14%) in the pre-COVID-19 group. In the ChAdOx1 nCov-19 group, 39 (21%) reported COVID-19 polymerase chain reaction tests were performed within 30 days of CVST symptom onset, and all were negative. Of the 117 patients with a reported outcome in the ChAdOx1 nCov-19 group, 44 (38%, 95% CI 29%-47%) had died, compared to 2/10 (20%, 95% CI 6%-51%) in the mRNA vaccine group and 3/100 (3%, 95% CI 1%-8%) in the pre-COVID-19 group. Mortality amongst patients with thrombocytopenia in the ChAdOx1 nCov-19 group was 49% (95% CI 39%-60%).
Conclusions:
Cerebral venous sinus thrombosis occurring after ChAdOx1 nCov-19 vaccination has a clinical profile distinct from CVST unrelated to vaccination. Only CVST after ChAdOx1 nCov-19 vaccination was associated with thrombocytopenia.
Keywords:
COVID-19 vaccine; CVST; EMA; thrombocytopenia.
© 2021 The Authors. European Journal of Neurology published by John Wiley & Sons Ltd on behalf of European Academy of Neurology.
This work received no specific grant from any fundingagency in the public, commercial, or not‐for‐profit sectors. All authors have completed the ICMJE uniform disclosure form. KK, MSK, TH, SMS, MML, KJ and JAKH have nothing to disclose. MRH reports grants from the Swiss Heart Foundation and Bangerter Foundation, travel support from Bayer, and Advisory Board honoraria from Amgen, and being a member of the ESO Board of Directors and of the ESO Education Committee. EL reports academic grants from the Swedish Neurological Society, Elsa and Gustav Lindh's Foundation, P‐O Ahl's Foundation and Rune and Ulla Amlöv's Foundation. TT reports academic grants from Sahlgrenska University Hospital, University of Gothenburg, Sigrid Juselius Foundation, Wennerström Foundation and European Union; advisory board membership/steering committee membership Bayer, Bristol Myers Squibb, Boehringer Ingelheim and Portola Pharma, lecture honorarium from University of Krems, Austria; all outside the submitted work. JP reports grants paid to his institution from the Academy of Finland, Hospital District of Helsinki and Uusimaa, and Finnish Foundation for Cardiovascular Research, consulting fees from Boehringer‐Ingelheim, Bayer and Herantis Pharma, payment for honoraria, lectures, presentations, speakers bureaus, manuscript writing or educational events from Boehringer Ingelheim, Bayer and Abbot, and stock ownership in Vital Signum. DAS reports travel support from Boehringer Ingelheim, DSMB participation for the SECRET trial, and being a member of the ESO Executive Committee. SM reports grants from Bayer paid to her institution, personal fees from Bayer paid to her institution, grants from Pfizer paid to her institution, personal fees from BMS/Pfizer paid to her institution, grants from Boehringer Ingelheim paid to her institution, personal fees from Boehringer Ingelheim paid to her institution, personal fees from Abbvie paid to her institution, personal fees from Portola/Alexion paid to her institution, grants from Daiichi Sankyo paid to her institution, and personal fees from Daiichi Sankyo paid to her institution, outside of the submitted work. MA reports honoraria for lectures from Bayer, AstraZeneca, Covidien and Medtronic, and honoraria for scientific advisory board participation from Amgen, Bayer, BMS, Daiichi Sankyo, Medtronic and Novartis. JMC reports grants paid to his institution from Boehringer Ingelheim and Bayer, and payments paid to his institution for DSMB participation by Bayer. JMF reports fees and DSMB or advisory board participation for Boehringer Ingelheim and consulting fees from Bayer. No other relationships or activities that could appear to have influenced the submitted work.
It’s sad to see anyone harmed by a vaccine or medication. But I’ll ask you the same. How many people should die, spend weeks in a hospital, suffer lifelong health damage, or grieve for lost loved ones needlessly because they didn’t bother to be vaccinated?
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False premise because, as studies and evidence from the UK and Israel have shown, there is no relative benefit to getting vaccinated. You are even more likely to get COVID-19 or one of its variants if you have been vaccinated.
Not just that….to answer phoneyman’s absurd “turnaround” question…..
First, we know the CDC death counts were admittedly altered.
Yet, how many ‘died, spent weeks hospitalized, suffered lifelong health damage, or grieved for lost loved ones needlessly because’ the evil PTB would not allow PROVEN, SAFE and EFFECTIVE EARLY TREATMENTS??
Didn’t bother to be vaccinated???? Seriously??
From an INEFFECTIVE (at preventing death, or hospitalization, anyway) shot that’s caused over 16,000 deaths (that they’ve allowed to be reported) and, hundreds of thousands adverse effects?
So, again, I ask you….how many deaths, from these hazardous shots are “acceptable” to you?
You (falsely) said, upthread, that there are “very few cases”.
Liberals will never say how much welfare is enough, nor how many clot shot deaths are acceptable.
Sorry but, your facts are wrong. The death rates among the vaccinated are FAR lower. Data from the UK and Israel show this very clearly.
Here is a similar US study, with the J&J vaccine:
US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021
https://pubmed.ncbi.nlm.nih.gov/33929487/
And a Pfizer one: Cerebral Thrombosis after the Pfizer Covid-19 Vaccine
https://drjessesantiano.com/cerebral-thrombosis-after-the-pfizer-covid-19-vaccine/
He’s struggling with the dilemma of being beholden to a rationale under which he exposed his whole family to the jab.
Thus there will be no rational statement forthcoming.
I equate it to the guy in Close Encounters of the Third Kind who was counting Pepsi commercials:
Snorkle a gutteral laugh and pound a beer or a shot every time #13 comes around (they always will).
Not the most recent data from the UK.
Bothe the hospil8zations and deaths are mostly the vaccinated.
this is pretty interesting:
“Thrombocytopenia was reported.. in none in the mRNA vaccine group (0%, 95% CI 0%-13%) and in 7/100 (7%, 95% CI 3%-14%) in the pre-COVID-19 group. 2/10 (20%, 95% CI 6%-51%) in the mRNA vaccine group [died] and 3/100 (3%, 95% CI 1%-8%) in the pre-COVID-19 group [died].”
Noone in mRNA vaccine group developed Thrombocytopenia. During the study 2 of the mRNA group died. During the same time 3 of the (control group) pre-covid group died and 7 of the AZ group died. mRNA had a better survival risk than background rate survival - 3/2.
I’d rather die than have a stroke.
Uh, yes. Practically EVERYONE in the UK is vaccinated. It makes total sense that most of the deaths would be among the vaccinated. But, the total number of deaths is MUCH lower than it was in the earlier waves. Like, 90% lower.
Same is happening everywhere where vaccines have been widely applied.
I share your skepticism about big Pharma. But, facts are facts. Vaccines dramatically lower death rates.
Considering they don't consider someone "vaccinated" until TWO WEEKS after the Jim Jones Jab, the numbers are suspicious.
As for its effectiveness, the number of "breakthrough" cases is exposing Fauxi's lies.
Covid is surging in Waterford, Ireland where 99.7 percent of adults are Fully Vaccinated
https://freerepublic.com/focus/f-bloggers/4003571/posts
Can’t blame the clot shot, for these Day 1 - 13, post jab deaths, if they weren’t *really* “vax”d.
How disgusting of these evil people.
Most of the deaths are from other things, but they tested positive. Government people told you that was how they were doing the count.
2nd, the hospitals refuse to give the ones who really have covid life-saving meds. They prefer to slowly kill them with ventilator$$.
https://www.worldometers.info/coronavirus/country/uk/
There’s nothing suspicious. Deaths are lower now than pre-vaccine.
Cases are going up again in the UK. They appear to have a new variant that spreads easily, even among the vaccinated. But death RATES remain low.
There is a ton of pure crap on the internet (and on FR) about Covid. We just try to get the facts right.
re: “How many people should die, spend weeks in a hospital, suffer lifelong health damage”
Had Covid-19 last year Aug-Sep time frame ... BACK TO BETTER THAN NORMAL now, a full year later. Oh, was 65 last year too ... but I’m not fat, exercise regularly and yes, I was short of breath during Covid-19 but I continued on (carried on normal activities, including bike riding) and licked it. A word to the wise: EAT RIGHT and exercise ...
Lol. Which highly credible news source told you that?
2nd, the hospitals refuse to give the ones who really have covid life-saving meds. They prefer to slowly kill them with ventilator$$.
You're sick. Let me tell you why someone is intubated. People are intubated because they have become simply too exhausted to continue to breathe unaided and will soon perish from heart failure. Not because doctors are trying to kill their patients. Sick
Yet another bogus internet rumor you, and a Texas State Senate, Senator fell for.
https://www.reuters.com/article/factcheck-covid-vaccine-animal-idUSL2N2NJ1IK
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