Posted on 05/09/2014 9:04:42 AM PDT by Oldpuppymax
The latest bad news concerns one more of the ill-fated thiazolidinediones (TZDs). This class of drugs was introduced in the late 1990s, and includes Avandia, Actos, and Rezulin. TZDs are PPAR-gamma agonists, meaning that they activate peroxisome proliferator-activated receptors, especially the “gamma” receptor. Such activation affects certain metabolic processes, and among other things, insulin resistance is reduced.
Rezulin—notoriously fast-tracked by FDA—was withdrawn from the market in 2000, in the wake of scores of liver failures and deaths. Pfizer, the manufacturer, was on the hook for upwards of $750 million in damages. At the time, Dr. Janet Woodcock, director of FDA’s drug evaluation center, said that Avandia and Actos, “[O]ffer the same benefits as Rezulin without the same risk. We are now confident that patients have...
(Excerpt) Read more at coachisright.com ...
Roux-n-y weight-loss surgery eliminates type 2 diabetes, in most cases, and quickly. Heard it from the surgeon, and have seen it happen with 2 other patients in my Exercise/Cardiac Rehab class. If I had diabetes type 2, that would be my move.
Interestingly, they don’t know WHY the surgery eliminates type 2 diabetes. But it’s been observed, regularly enough that the surgeon who performed my Sleeve Gastrectomy says he is the diabetes-killer.
What does the surgery entail?
My wife’s numbers were higher than we liked so we seriously moderated the carb intake (she carefully, me mostly at family meals, I still cheat as I have good sugar numbers and limited self restraint with Penn Station french fries). However, just going along with her, albeit to a lesser degree, I have gone from 190 to 180 with no effort at all.
She also exercises for 1/2 hour every night. The dirty little secret is that exercise will drop your sugar numbers faster than anything else.
Interestingly, we both think she has lost a little more weight than we’d like, but it is not easy to put a few pounds back on when seriously limiting carbs.
We eat lots of vegetables and normal levels of protein and fat.
Now, I may be mistaken, but as I understand diabetes, you have it or you don’t. “Type 2” isn’t really diabetes, it’s a creation of the medical establishment to focus on theoretically potential future diabetics with the goal to prevent them from progressing to diabetes. But it is not diabetes. I can’t swear to that, but I believe it.
Is there justice when the laws are unjust?
Good for you. You are doing the correct method to best balance your metabolism, live long and remain healthy. Fatigued muscle is thirsty for sugar. Work them, and blood sugar stabilizes. Remove carbs, eat plenty of vegetables and increase protein 15-25%, while increasing dietary, unadulterated fat and blood sugar will remain stable.
LOL. Is that lower sugar production before or after the Big Mac and french fry munchie attack?
In HS I was unable to gain a pound regardless of effort. I went off to college, smoked a boatload of pot my first quarter, necessitating runs every night (after a dinner of dorm food) to the local Burger King for some serious shoveling in of Whoppers and fries. Result was I gained 15 pounds in 11 weeks.
Hmmm....I started seriously limiting carbs....doing interval training 3x week, pilates, and weights...and intermittent fasting...and my blood sugar went UP...(I lost 20lbs in about 7 months)...now seem to be at a standstill...and the doc says I MUST eat SOMETHING every 3-4 hours (usually I eat raw nuts)...to prevent the spike in blood sugar. I would like my fat % to drop another 6% (lose another 10 lbs maybe, too)....but, am not sure what I’m doing wrong.
Maybe you should have picked the right parents before you were born. Just kidding, of course. The body is complex and we are stuck with the genes we were given. Sometimes there is no explanation for why "a" works for one person and not another.
My wife got a monitor on her own and measured sugar to see what was most effective and what seemed to affect her the most in either direction. That was very useful in diet adjustments and routine.
One reason for doing that was her A1C was on the high side, even after her glucose tests got to normal. The A1C by itself should not be the determining factor for a couple of interesting reasons.
Ping!
Thx...yeah, those “genes”....I have been thinking about getting a monitor...I would like to know WHICH foods make it spike, or if it is Lack of food...like they are telling me...(hyperglycemia) My A1c was 5.4 I think, which I think is a little high....Did your wife find a decently priced monitor on her own, or thru insurance?
Type one and type two are both diabetes. Type one is juvenile diabetes and is caused by non functioning isles of Langerhans which make insulin
Type two diabetes is caused by malfunctioning feedback systems to the isles of Langerhans and resistance to the insulin they excrete. Type two can, with work be controlled by diet and exercise in some people.
monitors are cheap, the testing strips etc are expensive.
Thanks for that info.
Still, it sure seems to me that there are a lot of people being statistically classified as type 2 that are not really type 2.
Anyone can have spikes and drops by eating improperly. That doesn’t make them diabetic.
Walgreens has a cheap (about $20) monitor. I order the compatible strips from a supplier on Amazon for a pretty reasonable price. We’ve not bothered with prescriptions or using our ($5K deductible) insurance.
I don’t have the details in front of me, if you like I will look it up and post it or send it to you.
Thanks...I’ll look it up and check it out.
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