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Medical Madoff: Data Faked in 21 Studies
NN&V ^ | 3/10/09 | Nuke

Posted on 03/10/2009 7:38:38 PM PDT by grandpa jones

Over the past 12 years, anesthesiologist Scott Reuben revolutionized the way physicians provide pain relief to patients undergoing orthopedic surgery for everything from torn ligaments to worn-out hips. Now, the profession is in shambles after an investigation revealed that at least 21 of Reuben’s papers were pure fiction, and that the pain drugs he touted in them may have slowed postoperative healing.

“We are talking about millions of patients worldwide, where postoperative pain management has been affected by the research findings of Dr. Reuben,” says Steven Shafer, editor in chief of the journal Anesthesia & Analgesia, which published 10 of Reuben’s fraudulent papers.


TOPICS: Science
KEYWORDS: fraud; medicalresearch
The fraudulent data resulted in the sale of billions of dollars of COX2 inhibitors, including Vioxx, and Celebrex. Anesthesia & Analgesia editors say in hindsight, “it should have been a “red flag” that Reuben’s studies were consistently favorable to the drugs he studied.”

It seems to be a sign of the times that red flags have been continuously ignored for years in many fields of commerce.

1 posted on 03/10/2009 7:38:38 PM PDT by grandpa jones
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To: grandpa jones

Most folks I’ve talked to say the COX2 stuff really worked.

They miss them.


2 posted on 03/10/2009 7:48:26 PM PDT by Wiseghy ("You want to break this army? Then break your word to it.")
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To: grandpa jones

Hey, radiation treatment ain’t that bad if you have a doobie.


3 posted on 03/10/2009 7:49:29 PM PDT by Westlander (Unleash the Neutron Bomb)
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To: grandpa jones

Scott Reuben

4 posted on 03/10/2009 7:51:46 PM PDT by kcvl
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To: grandpa jones

In addition to allegedly falsifying data, Dr. Reuben seems to have committed publishing forgery. Evan Ekman, MD, an orthopedic surgeon in Columbia, S.C., said his name appeared as a co-author on at least two of the retracted papers, despite his having had no hand in the manuscripts. “My names were forgeries on the documents,” Dr. Ekman told Anesthesiology News.


5 posted on 03/10/2009 7:53:18 PM PDT by kcvl
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To: grandpa jones

Schmuck!


6 posted on 03/10/2009 7:53:45 PM PDT by Wally_Kalbacken
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To: kcvl

Guilty


7 posted on 03/10/2009 7:54:15 PM PDT by Blogger (Pray and Prepare)
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To: grandpa jones

“Dr. Reuben deeply regrets that this happened,” said the doctor’s attorney, Ingrid Martin. “Dr. Reuben cooperated fully with the peer review committee. There were extenuating circumstances that the committee fairly and justly considered.” She declined to explain the extenuating circumstances. Dr. Reuben didn’t respond to requests for comment sent through Ms. Martin and left at his former office.

Dr. Reuben had been a paid speaker on behalf of Pfizer’s medicines, and it paid for some of his research. “It is very disappointing to learn about Dr. Scott Reuben’s alleged actions,” Pfizer said in a statement. “When we decided to support Dr. Reuben’s research, he worked for a credible academic medical center and appeared to be a reputable investigator.”

Hal Jenson, the chief academic officer at Baystate Medical, said a routine audit last spring flagged discrepancies in Dr. Reuben’s work. That led to a larger investigation in which Dr. Reuben cooperated, Dr. Jenson said. “The conclusions are not in dispute,” he added.

Dr. Reuben is on an indefinite leave from his post at Baystate, the hospital said. He no longer holds an appointment as a professor at Tufts University’s medical school, according to the university.


8 posted on 03/10/2009 7:55:56 PM PDT by kcvl
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To: kcvl

Could be a doofus.


9 posted on 03/10/2009 8:01:39 PM PDT by popdonnelly (It's fair to ask: did the voters elect a nut?)
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To: grandpa jones

Vioxx worked. Take it from someone who knows. Me. Too bad it had such a bad effect on blood pressure. :-(


10 posted on 03/10/2009 8:06:11 PM PDT by oldvike
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To: oldvike

I know. My wife misses it


11 posted on 03/10/2009 8:10:03 PM PDT by grandpa jones (L.O.M.A. (loyal opposition my azz))
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To: popdonnelly
Hey, this guy is involved with versed (Midazoliam) as well. Bunch of references ~ because, it turns out, Midazoliam is frequently administered to patients who receive the other drugs.

http://psyweb.com/Drughtm/jsp/versed.jsp carries a warning for versed I don't recall seeing before.

Could be related to this particular problem.

12 posted on 03/10/2009 8:15:46 PM PDT by muawiyah
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To: Wiseghy

I took celebrex for a short time to get acute pain under control while working to fix the problem long-term through physical therapy. It was a lifesaver.

Like you, I also know people who can get relief from nothing else.


13 posted on 03/10/2009 8:29:33 PM PDT by freespirited (The trouble with socialism is that you eventually run out of other people's money. -- M. Thatcher)
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To: oldvike

That’s good for you, but it killed my 54 year old Aunt. Her kids miss her.


14 posted on 03/10/2009 8:46:19 PM PDT by bluecollarman
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To: neverdem
Like, *PING*, dude.

Who are the MD's on Free Republic? I have a hunch they'll find this interesting.

Cheers!

15 posted on 03/10/2009 9:16:07 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: grey_whiskers
My uncle was an anesthesiologist and he wouldn't take anything. He died of cancer and refused pain meds--he didn't want to get addicted...on his deathbed didn't make sense to me. I wish now I had asked him more about it...I think maybe he had seen a lot.

My mother asked him for a prescription for Valium before it was known to be addictive. She not only didn't get the Rx, she got a sermon about taking it. That one he was right about.

16 posted on 03/10/2009 9:41:04 PM PDT by lonestar (Obama has turned a crisis into a catastrophe.)
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To: grey_whiskers; All
WTF... millions of patients involved, and all based on one guys studies, paid for by the drug manufacturer!

Doesn't the medical industry use back-up studys with experiments repeated by different researchers?

Most other scientific fields do this.

Perhaps that why medicine is an “art”....:^)

17 posted on 03/10/2009 9:43:09 PM PDT by az_gila (AZ - need less democrats - one Governor down... more to go.)
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To: AdmSmith; Berosus; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; george76; ...
Doctor's Pain Studies Were Fabricated, Hospital Says
by Gardiner Harris
Published: March 10, 2009
Correction Appended

18 posted on 03/25/2009 6:25:49 PM PDT by SunkenCiv (https://secure.freerepublic.com/donate/____________________ Profile updated Monday, January 12, 2009)
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