Posted on 06/08/2019 10:42:55 PM PDT by Rabin
Physical work.
Interesting, my guess is that it will not detoxify vitamin E and interfere with its blood thinning effect. That is d-alpha tocopherol, not L-alpha or DL-alpha.
Is K2 named after the famous mountain?
Is K2 named after the famous mountain?
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Nooo. Did you see what they did to K1?
All: (from the wiki)
Vitamin K2 has only begun to be studied, and the few studies on humans suffer from a small sample size or no reproduced results by an independent team. Reports from northern Japan correlate vitamin K consumption with improved bone health.
The possible health benefits suggested for further investigation relate to bone strength and arterial health (reducing calcification or even decalcifying, with a possible reduction in blood pressure).
The U.S. Food and Drug Administration (FDA) has not approved any form of vitamin K for the prevention or treatment of osteoporosis. MK-4 (45 mg daily) has been approved by the Ministry of Health in Japan since 1995 for the prevention and treatment of osteoporosis.
Sure.
“Prostaglandin, a potent bone-resorbing agent, is synthesized in osteoblast-like cells. Since vitamin K reportedly plays an important role in (viscosity, clotting &) bone metabolism, we investigated the effects of vitamin K2 (menatetrenone) on PGE2 production by human osteoblast-like periosteal cells. “
The above is the background and introduction. Prostaglandin is made in bone cells and is a bone resorbing agent. Bone resorbtion releases calcium in to the blood.
This vitamin, chemical name menatetrenone, is known to affect bone metabolism, so they did experiments to see if it affects production if prostaglandins in bone cells. It specifies the cells used for the experiments, periosteal cells. (The experiments are done with cells in culture).
“In cells incubated with menatetrenone (1 microgram/mL = 2.25 x 10(-6) M) for 2 days, PGE2 production was reduced to 50% of that in untreated control cells.”
When cells were grown with the vitamin, prostaglandin E2 synthesis was decreased by half. The concentration of vitamin and length of exposure time are given.
The next experiments look at the mechanism whereby prostaglandin synthesis was inhibited.
“In one of these menatetrenone at doses of 0.5-10 micrograms/mL dose dependently inhibited the calcium ionophore A23187-induced release of arachidonic acid (AA) from membrane phospholipids, and in the other the conversion of AA to PG was inhibited, as evidenced by the PG-synthesizing activity in the homogenates of menatetrenone-treated cells with AA being lower than that in untreated cells. The inhibitory effect was almost identical to that for PG production.”
The vitamin caused two steps in the process of synthesizing prostaglandin to be affected, the release of arachidonic acid and enzymatic reaction that turns it in to prostaglandin. These inhibitory responses were dose-dependent, meaning the more vitamin added to the cell culture, the greater the inhibition.
“This study shows that menatetrenone inhibited PGE2 release from cells by inhibiting both PG production steps, AA release from the membrane and PG synthesizing activity with AA. Inhibition of PGE2 production by menatetrenone might be important in improving bone metabolism.”
This concluding section reiterates the findings and suggests a possible use for the vitamin.
Compared to US EPA’s Clean Air Act regulations, it is very clear. But then, so is mud, six inches of oak plank, or a heavy fog at midnight and no moon. Some things are so relative, they don’t fit the scale.
Hahaha... why didn’t I think of that! /s
Coumadin (Warfarin) https://www.kfreedaily.com/vitamin-k-and-anticoagulants/
I’m pretty sure I read the same thing, decades ago, when I was trying to program my VCR.
Yes here’s what K2 does it takes the calcium in your system and pushes it directly into your bones. The reason you take K2 together with D3 is that the D3 helps the calcium absorb into your system then the K2 pushes it into your bones.
Older people should be taking K2 because it keeps calcium from getting into your arteries and clogging them up.
Good catch and WTF? What we need is a way to stop or slow the shortening of our cells' telomeres - the process that dictates our slow breakdown and eventual demise. No regimen of exercise, nutrition, fad therapies or sucking fetus blood (Hillary) will stop it.
What’s not clear? Specifically.
I’m thinking maybe the concentration terminology.
I’ll explain specific things.
Cut and paste.
How would someone named Finnegan even know what babble is? ;)
Right. Vitamin k2 is Magic for bones and teeth. Dr. Weston A Price discovered that 100 years ago.
No, it really is clear. Some hard things are clear, nonetheless.
I was more putting down the EPA Clean Act Act regulations. They are hard, primarily because they are not clear.
OK, that’s funny right there...
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