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Word For The Day, Thursday, 6/27/02
The Verbivores | 6/27/02 | Teacher

Posted on 06/27/2002 7:19:53 AM PDT by RikaStrom

In order that we might all raise the level of discourse and expand our language abilities, here is the daily post of “word for the day”. Rules: Everyone must leave a post using the “word of the day”; in a sentence. The sentence must, in some way, relate to the news of the day. The Review threads are linked for your edification. ;-) Practice makes perfect.....post on....


fulminate \FUL-muh-nayt\, intransitive verb, transitive verb:
fulminates, fulminating; fulminated
fulmination, fulminator; noun
fulminatory; adjective

1. To issue or send forth decrees or censures with the assumption of supreme authority; to thunder forth menaces.
2. To thunder; hence, to make a loud, sudden noise; to detonate; to explode with a violent report.
3. To utter or send out with denunciations or censures.
4. To cause to explode.
5. An explosive salt of fulminic acid, especially fulminate of mercury
They fulminated the most hostile of all decrees. --De Quincey.

Etymology: Middle English, from Medieval Latin fulminatus, past participle of fulminare, from Latin, to strike (of lightning), from fulmin-, fulmen lightning; akin to Latin flagrare to burn. Date: 15th century.



TOPICS: Education; Humor; Word For The Day
KEYWORDS: 62702; students; thursday; wordfortheday
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To: hobbes1
what in the heck is that?
241 posted on 06/28/2002 6:03:52 AM PDT by xsmommy
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To: hobbes1
ok, i saw the thread. no way that kid looks palestinian!
242 posted on 06/28/2002 6:04:45 AM PDT by xsmommy
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To: xsmommy
I thought the same thing....
243 posted on 06/28/2002 6:04:59 AM PDT by hobbes1
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To: hobbes1
Who's getting fingered in here???
Consenting adults, I assume?
244 posted on 06/28/2002 6:09:04 AM PDT by TheGrimReaper
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To: TheGrimReaper; xsmommy; CholeraJoe
According to xsexmommy, it's CJ...
245 posted on 06/28/2002 6:10:09 AM PDT by hobbes1
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To: hobbes1
And why is that a Prescription Drug anyway...

Fetal toxicity

Animal Fetotoxicity

Oral administration of clomiphene citrate to pregnant rats during organogenesis at doses of 1-2 mg/kg/day resulted in hydramnion and weak, edematous fetuses with wavy ribs and other temporary bone changes. Doses of 8 mg/kg/day or more also caused increased resorptions and dead fetuses, dystocia, and delayed parturition, and 40 mg/kg/day resulted in increased maternal mortality. Single doses of 50 mg/kg caused fetal cataracts, while 200 mg/kg caused cleft palate.

Following injection of clomiphene citrate 2 mg/kg to mice and rats during pregnancy, the offspring exhibited metaplastic changes of the reproductive tract. Newborn mice and rats injected during the first few days of life also developed metaplastic changes in uterine and vaginal mucosa, as well as premature vaginal opening and anovulatory ovaries. These findings are similar to the abnormal reproductive behavior and sterility described with other estrogens and antiestrogens.

In rabbits, some temporary bone alterations were seen in fetuses from dams given oral doses of 20 or 40 mg/kg/day during pregnancy, but not following 8 mg/kg/day. No permanent malformations were observed in those studies. Also, rhesus monkeys given oral doses of 1.5-4.5 mg/kg/day for various periods during pregnancy did not have any abnormal offspring.

Can't sell anything over the counter that deforms fetuses. Remember thalidomide or were you too young?

246 posted on 06/28/2002 6:10:17 AM PDT by CholeraJoe
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To: CholeraJoe
Too young, but the story rings a bell.
247 posted on 06/28/2002 6:11:04 AM PDT by hobbes1
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To: hobbes1
baby!
248 posted on 06/28/2002 6:11:45 AM PDT by xsmommy
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To: CholeraJoe
Single doses of 50 mg/kg caused fetal cataracts, while 200 mg/kg caused cleft palate.

Aren't those rather huge dosages...or am I reading that wrong?

249 posted on 06/28/2002 6:12:11 AM PDT by hobbes1
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To: CholeraJoe
Though that would also explain the limited prescriptions given to women trying to achieve fertility....Thanx Doc!

250 posted on 06/28/2002 6:16:17 AM PDT by hobbes1
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To: xsmommy
So what if I am...That turn you on Mrs.Robinson?
251 posted on 06/28/2002 6:16:49 AM PDT by hobbes1
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To: hobbes1
In animal studies, they always use huge doses. Normal dose in humans is 25-50 mg/day.
252 posted on 06/28/2002 6:16:49 AM PDT by CholeraJoe
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To: CholeraJoe
It just irks me that things aging men can use, to help combat said process, are all prohibited, in one way or another....
253 posted on 06/28/2002 6:17:59 AM PDT by hobbes1
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To: hobbes1
Though that would also explain the limited prescriptions given to women trying to achieve fertility

Actually this is what explains the limitation on quantity prescribed to women.

Ovarian Hyperstimulation Syndrome

The ovarian hyperstimulation syndrome (OHSS) has been reported to occur in patients receiving clomiphene citrate therapy for ovulation induction. In some cases, OHSS occurred following cyclic use of clomiphene citrate therapy or when clomiphene citrate was used in combination with gonadotropins. Transient liver function test abnormalities suggestive of hepatic dysfunction, which may be accompanied by morphologic changes on liver biopsy, have been reported in association with ovarian hyperstimulation syndrome (OHSS).

OHSS is a medical event distinct from uncomplicated ovarian enlargement. The clinical signs of this syndrome in severe cases can include gross ovarian enlargement, gastrointestinal symptoms, ascites, dyspnea, oliguria, and pleural effusion. In addition, the following symptoms have been reported in association with this syndrome: pericardial effusion, anasarca, hydrothorax, acute abdomen, hypotension, renal failure, pulmonary edema, intraperitoneal and ovarian hemorrhage, deep venous thrombosis, torsion of the ovary, and acute respiratory distress. The early warning signs of OHSS are abdominal pain and distention, nausea, vomiting, diarrhea, and weight gain. Elevated urinary steroid levels, varying degrees of electrolyte imbalance, hypovolemia, hemoconcentration, and hypoproteinemia may occur. Death due to hypovolemic shock, hemoconcentration, or thromboembolism has occurred. Due to fragility of enlarged ovaries in severe cases, abdominal and pelvic examination should be performed very cautiously. If conception results, rapid progression to the severe form of the syndrome may occur.

254 posted on 06/28/2002 6:20:27 AM PDT by CholeraJoe
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To: hobbes1
does your mommy know you are posting to this thread ; ) ?
255 posted on 06/28/2002 6:20:46 AM PDT by xsmommy
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To: CholeraJoe
yikes! is this all the crap that they make you sign on the informed consent forms? you might die if we do this, but we will not be liable for it, because you know dang well you might die if we do this, and besides that if we lose or dent your car while in the parking garage, we aren't liable for that either.....
256 posted on 06/28/2002 6:23:24 AM PDT by xsmommy
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To: xsmommy
My parents are away for the weekend.. ; )
257 posted on 06/28/2002 6:24:53 AM PDT by hobbes1
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To: hobbes1
Clomid hasn't been tested enough in men to determine either its safety or efficacy. Notwithstanding multiple uncontrolled trials demonstrating high fertility when taken by men, the controlled studies don't prove effectiveness well enough to convince the FDA that it's effective. It can still be prescribed for men but it could be risky.
258 posted on 06/28/2002 6:25:15 AM PDT by CholeraJoe
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To: CholeraJoe
Just like Voting, damn women screw it up for the rest of us...
259 posted on 06/28/2002 6:25:28 AM PDT by hobbes1
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To: hobbes1
%&*@ Title IX!
260 posted on 06/28/2002 6:26:32 AM PDT by CholeraJoe
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