The virus is similar to COVID-19 in that it attacks the endothelial cells of the inner wall of the blood vessels. The main difference is that it doesn't bind with the ACE2 receptors - it binds with the αvβ3 (the vitronectin receptor) on endothelial cells — this is the dominant entry point driving vascular pathology. This, too, leads to oxidative stress.
The other difference is that while COVID-19 has a 3-5 day incubation period before symptoms occur, hantavirus has a 1-5 week gestation period.
This suggests to me (and AI concurs) that the same treatment for COVID-19 would work with hantavirus:
- Quercetin + Zinc to inhibit RNA-dependent RNA polymerase (RdRp), the replication of the RNA in the infected cell. This slows down the spead of the virus during its dormant period.
- Vitamin C increases the effectiveness of quercetin as a zinc ionophore.
- Vitamin D3 treats the inflammation of the endothelial cells.
- NAC produces glutathione and prevents oxidative stress.
If someone thinks they were exposed to the hantavirus, they should begin this regimen immediately. See this link
for my COVID-19 regimen.
The caution is that once the hantavirus expresses itself, the impacts are much more severe and quicker than COVID-19.
-PJ
You know that your preventative immune system regimen may have helped me too. Since Covid I take Vitamin C, D3, zinc and Quercetin daily. This year I avoided serious, high temperature flu (no shots either) and had no colds but just an occasional sore throat and my allergies to deal with. If I had been exposed to the hantavirus my immune system may have been strong enough to prevent it from developing into something much more serious. Speculation only.