Targeted vitamin D3 supplementation cuts risk of second heart attack in half, study finds

Medical Xpress / Intermountain Healthcare / ^ | Nov. 9, 2025

[ConservativeMind]

At 40 ng/mL of vitamin D in the blood, all cardiac events were cut in half.

85% of people with cardiac events had less than that, prior to receiving the vitamin D in this study.

Yes, you should know if you have adequate vitamin D, even if only checked one time, unless you can surmise you already get enough.

[ConservativeMind]

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[for-q-clinton]

What about D2?

[decal]

Or WD-40?

[KittyKares]

D3 was even important in keeping one from getting a bad case of Covid, as I recall. I’m finding that Vitamin D is important for more aspects of health than I realized, especially since the levels seem to decline in old age.

[ConservativeMind]

Nearly everything I read says it’s best to only take vitamin D3.

[ConservativeMind]

My one vitamin D test showed I had 36 ng/mL.

I would be a little low, on this concern.

[for-q-clinton]

I looked it up and yes “best” for D3, but D2 works but D3 is just a bit better. D2 is for vegans who don’t want anything from animals.

[The Duke]

As I understand it, D2 gets turned into D3 in the body, however taking D3 directly ends up being more cost-effective.

[Uncle Miltie]

“40 nanograms per ml (ng/mL)”

Checking in at 63 myself. Two Costco sized gelcaps per day, one each in the morning and evening.

[catnipman]

“What about D2?”

vitamin D1 is actually the active form: D3 is converted to D2 in the body and then D2 is converted into D1 under control of the parathyroid gland because too much D1 is deadly, which is why it’s difficult to OD on D3 for those with a normally functioning parathyroid gland ...

[sauropod]

Been taking D3 for years.

[Red Badger]

I take 5000+ IUs every day...........

[JohnnyP]

Mine was in the low ‘90’s one year. The PA said that’s too high, and to back off on the capsules.

I was taking 20,000 IU’s a day. :)

[MomwithHope]

5000 in the winter, 1000 in the summer.

[Uncle Miltie]

Grok: “ Understanding Vitamin D Levels Vitamin D status is assessed by measuring serum 25-hydroxyvitamin D [25(OH)D] levels in the bloodstream, typically in nanograms per milliliter (ng/mL) or nanomoles per liter (nmol/L; 1 ng/mL ≈ 2.5 nmol/L). The “optimal” level refers to the concentration associated with the best health outcomes, including bone health, fracture prevention, immune function, and reduced risk of chronic diseases like cancer, cardiovascular issues, and diabetes. However, definitions vary due to differences in study populations, endpoints, and guidelines. Scientific consensus distinguishes: • Deficiency: <20 ng/mL (<50 nmol/L) – Linked to rickets, osteomalacia, secondary hyperparathyroidism, and increased fracture risk. • Insufficiency: 20–29 ng/mL (50–72.5 nmol/L) – May still pose risks for falls, bone loss, and suboptimal immune response. • Sufficiency/Optimal: ≥30 ng/mL (≥75 nmol/L) – Generally recommended for full health benefits. • Upper Limit: Levels >100–150 ng/mL (>250–375 nmol/L) risk toxicity (e.g., hypercalcemia), though sun exposure rarely causes this.”

[Ancesthntr]

That’s to lubricate your joints.

[montag813]

PLEASE make sure you use Vitamin D3 that your body can actually metabolize. The #1 best-absorbed D3 in ConsumerLab.com's tests was Bluebonnet. My father in law has seen dramatic improvement since his heart attack. I take this every morning after waking up.
It has the 5,000 I.U. this study recommends in a single drop:

Bluebonnet Nutrition Liquid Vitamin D3 Drops 5000 IU

P.S. Consumer Lab found a further 20% increase in absorption if taken before or after an oil-based food, such as fish or nuts.

[JohnnyP]

Thanks for the details on that. She was engaging in harmless fear mongering.

[BFW]

WD-40 is out, wrap wound with electrical tape after spraying with Windex.........

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